Sarcoma-Targeting Peptide-Decorated Polypeptide Nanogel Intracellularly Delivers Shikonin for Upregulated Osteosarcoma Necroptosis and Diminished Pulmonary Metastasis

Purpose: Osteosarcoma is the most common primary bone cancer and is notorious for pulmonary metastasis, representing a major threat to pediatric patients. An effective drug targeting osteosarcoma and its lung metastasis is urgently needed. Design: In this study, a sarcoma-targeting peptide-decorated...

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Detalles Bibliográficos
Autores principales: Li, Suoyuan, Zhang, Tao, Xu, Weiguo, Ding, Jianxun, Yin, Fei, Xu, Jing, Sun, Wei, Wang, Hongsheng, Sun, Mengxiong, Cai, Zhengdong, Hua, Yingqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835942/
https://www.ncbi.nlm.nih.gov/pubmed/29507626
http://dx.doi.org/10.7150/thno.18299

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