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The Emerging Role of Tractography in Deep Brain Stimulation: Basic Principles and Current Applications

Diffusion tensor imaging (DTI) is an MRI-based technique that delineates white matter tracts in the brain by tracking the diffusion of water in neural tissue. This methodology, known as “tractography”, has been extensively applied in clinical neuroscience to explore nervous system architecture and d...

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Detalles Bibliográficos
Autores principales: Rodrigues, Nelson B., Mithani, Karim, Meng, Ying, Lipsman, Nir, Hamani, Clement
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836042/
https://www.ncbi.nlm.nih.gov/pubmed/29382119
http://dx.doi.org/10.3390/brainsci8020023
Descripción
Sumario:Diffusion tensor imaging (DTI) is an MRI-based technique that delineates white matter tracts in the brain by tracking the diffusion of water in neural tissue. This methodology, known as “tractography”, has been extensively applied in clinical neuroscience to explore nervous system architecture and diseases. More recently, tractography has been used to assist with neurosurgical targeting in functional neurosurgery. This review provides an overview of DTI principles, and discusses current applications of tractography for improving and helping develop novel deep brain stimulation (DBS) targets.