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A Case of Erythema Multiforme Major Developed after Sequential Use of Two Immune Checkpoint Inhibitors, Nivolumab and Ipilimumab, for Advanced Melanoma: Possible Implication of Synergistic and/or Complementary Immunomodulatory Effects

Immune checkpoint inhibitors, such as ipilimumab and nivolumab, reverse the imbalance of antitumor self-tolerance and enhance T-cell responses. Currently, ipilimumab and nivolumab have a reported therapeutic impact on unresectable or metastatic melanomas; however, they also induce immune-related adv...

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Detalles Bibliográficos
Autores principales: Utsunomiya, Akira, Oyama, Noritaka, Iino, Shiro, Baba, Natsuki, Chino, Takenao, Utsunomiya, Natsuko, Hasegawa, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836162/
https://www.ncbi.nlm.nih.gov/pubmed/29515387
http://dx.doi.org/10.1159/000485910