Endoscopic versus Laparoscopic Full-Thickness Biopsy in the Pathological Evaluation of the Enteric Nervous System

A full-thickness biopsy of the bowel wall is required to evaluate the enteric nervous system. A patient with aggravating gastrointestinal symptoms underwent a laparoscopic full-thickness biopsy of the ileum and, 1 year later, an endoscopic full-thickness biopsy of the sigmoid colon. Both samples sho...

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Autores principales: Ohlsson, Bodil, Gustafsson, Rita J., Toth, Ervin, Veress, Bèla, Thorlacius, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2018
Materias:
Single Case
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836257/
https://www.ncbi.nlm.nih.gov/pubmed/29515343
http://dx.doi.org/10.1159/000486390
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author Ohlsson, Bodil
Gustafsson, Rita J.
Toth, Ervin
Veress, Bèla
Thorlacius, Henrik
author_facet Ohlsson, Bodil
Gustafsson, Rita J.
Toth, Ervin
Veress, Bèla
Thorlacius, Henrik
author_sort Ohlsson, Bodil
collection PubMed
description A full-thickness biopsy of the bowel wall is required to evaluate the enteric nervous system. A patient with aggravating gastrointestinal symptoms underwent a laparoscopic full-thickness biopsy of the ileum and, 1 year later, an endoscopic full-thickness biopsy of the sigmoid colon. Both samples showed enteric neuropathy characterized by vacuolated and enlarged neurons. The length of the myenteric plexus was greater in the endoscopic (23 mm) compared to the laparoscopic (11 mm) biopsy, with fewer tissue artefacts in the laparoscopic approach. Clinical deterioration was paralleled by enteric neuropathy with an increase in the percentage of vacuolated and enlarged enteric neurons from 24 to 35%.
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spelling pubmed-58362572018-03-07 Endoscopic versus Laparoscopic Full-Thickness Biopsy in the Pathological Evaluation of the Enteric Nervous System Ohlsson, Bodil Gustafsson, Rita J. Toth, Ervin Veress, Bèla Thorlacius, Henrik Case Rep Gastroenterol Single Case A full-thickness biopsy of the bowel wall is required to evaluate the enteric nervous system. A patient with aggravating gastrointestinal symptoms underwent a laparoscopic full-thickness biopsy of the ileum and, 1 year later, an endoscopic full-thickness biopsy of the sigmoid colon. Both samples showed enteric neuropathy characterized by vacuolated and enlarged neurons. The length of the myenteric plexus was greater in the endoscopic (23 mm) compared to the laparoscopic (11 mm) biopsy, with fewer tissue artefacts in the laparoscopic approach. Clinical deterioration was paralleled by enteric neuropathy with an increase in the percentage of vacuolated and enlarged enteric neurons from 24 to 35%. S. Karger AG 2018-01-19 /pmc/articles/PMC5836257/ /pubmed/29515343 http://dx.doi.org/10.1159/000486390 Text en Copyright © 2018 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Single Case
Ohlsson, Bodil
Gustafsson, Rita J.
Toth, Ervin
Veress, Bèla
Thorlacius, Henrik
Endoscopic versus Laparoscopic Full-Thickness Biopsy in the Pathological Evaluation of the Enteric Nervous System
title Endoscopic versus Laparoscopic Full-Thickness Biopsy in the Pathological Evaluation of the Enteric Nervous System
title_full Endoscopic versus Laparoscopic Full-Thickness Biopsy in the Pathological Evaluation of the Enteric Nervous System
title_fullStr Endoscopic versus Laparoscopic Full-Thickness Biopsy in the Pathological Evaluation of the Enteric Nervous System
title_full_unstemmed Endoscopic versus Laparoscopic Full-Thickness Biopsy in the Pathological Evaluation of the Enteric Nervous System
title_short Endoscopic versus Laparoscopic Full-Thickness Biopsy in the Pathological Evaluation of the Enteric Nervous System
title_sort endoscopic versus laparoscopic full-thickness biopsy in the pathological evaluation of the enteric nervous system
topic Single Case
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836257/
https://www.ncbi.nlm.nih.gov/pubmed/29515343
http://dx.doi.org/10.1159/000486390
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