Cargando…

Successful Resection of G719X-Positive Pleomorphic Carcinoma after Afatinib Treatment

We report a case of pleomorphic carcinoma with exon 18 mutation (G719X) of the epidermal growth factor receptor (EGFR), which showed good response to afatinib and resulted in successful resection. To our knowledge, this is the first report on the use of afatinib for pleomorphic carcinoma followed by...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nakamura, Daisuke, Miura, Kentaro, Kumeda, Hirotaka, Agatsuma, Hiroyuki, Hyogotani, Akira, Hamanaka, Kazutoshi, Koizumi, Tomonobu, Yamamoto, Hiroshi, Tamada, Hisashi, Ito, Ken-ichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	S. Karger AG 2017
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836259/ https://www.ncbi.nlm.nih.gov/pubmed/29515394 http://dx.doi.org/10.1159/000480120

Ejemplares similares

Primary mediastinal dedifferentiated liposarcoma: Five case reports and a review
por: Miura, Kentaro, et al.
Publicado: (2018)

Bone morphogenetic protein-7 expression reflects the high proliferative ability and aggressiveness of thymic epithelial tumors
por: Miura, Kentaro, et al.
Publicado: (2020)

Solid component tumor doubling time is a prognostic factor in non-small cell lung cancer patients
por: Miura, Kentaro, et al.
Publicado: (2019)

Development of angiosarcoma in a mediastinal non‐seminomatous germ cell tumor that exhibited growing teratoma syndrome during chemotherapy
por: Matsuoka, Shunichiro, et al.
Publicado: (2018)

Successful resection after first‐line lenvatinib therapy in an advanced thymic carcinoma
por: Shimura, Masatoshi, et al.
Publicado: (2023)

Exceptional response to afatinib in a patient with persistent G719A EGFR-mutant NSCLC
por: Kulkarni, Amit A, et al.
Publicado: (2022)

FGF2-FGFR1 pathway activation together with thymidylate synthase upregulation is induced in pemetrexed-resistant lung cancer cells
por: Miura, Kentaro, et al.
Publicado: (2019)

The Effectiveness of Afatinib in a Patient with Advanced Lung Adenocarcinoma Harboring Rare G719X and S768I Mutations
por: Watanabe, Masahiro, et al.
Publicado: (2017)

Successful afatinib rechallenge in a patient with non‐small cell lung cancer harboring EGFR G719C and S768I mutations
por: Masuda, Tomomi, et al.
Publicado: (2020)

Clinical analysis of EGFR‐positive non‐small cell lung cancer patients treated with first‐line afatinib: A Nagano Lung Cancer Research Group
por: Sonehara, Kei, et al.
Publicado: (2019)

Surgical outcomes in patients with small cell lung cancer: comparative analysis of computed tomograpy-detected patients with others
por: Koizumi, Tomonobu, et al.
Publicado: (2013)

Response to: Successful afatinib rechallenge in a patient with non‐small cell lung cancer harboring EGFR G719C and S768I mutations
por: Citarella, Fabrizio, et al.
Publicado: (2021)

Rechallenge of afatinib for EGFR-mutated non-small cell lung cancer previously treated with osimertinib: a multicenter phase II trial protocol (REAL study)
por: Araki, Taisuke, et al.
Publicado: (2023)

Tumor Size and Computed Tomography Attenuation of Pulmonary Pure Ground-Glass Nodules Are Useful for Predicting Pathological Invasiveness
por: Eguchi, Takashi, et al.
Publicado: (2014)

Poster Sessions 555 - 719
Publicado: (2003)

A rare case of double primary lung adenocarcinomas with uncommon complex EGFR G719X and S768I mutations and pleomorphic carcinoma
por: Morimoto, Toshiki, et al.
Publicado: (2023)

Afatinib for Advanced Non-small Cell Lung Cancer in a Case With an Uncommon Epidermal Growth Factor Receptor Mutation (G719A) Identified in the Cerebrospinal Fluid
por: Ma, Chunhua, et al.
Publicado: (2019)

Resected Pleomorphic Carcinoma of the Gallbladder
por: Shimada, Masanari, et al.
Publicado: (2012)

Adoption of Robotic Core Technology in Minimally Invasive Lung Segmentectomy: Review
por: Eguchi, Takashi, et al.
Publicado: (2022)

Robotic segmentectomy using a lung base-flip approach
por: Eguchi, Takashi, et al.
Publicado: (2022)

Harnessing 3D-CT Simulation and Planning for Enhanced Precision Surgery: A Review of Applications and Advancements in Lung Cancer Treatment
por: Hamanaka, Kazutoshi, et al.
Publicado: (2023)

Anterior Uveitis Caused by Ocular Side Effects of Afatinib: A Case Report
por: Todokoro, Daisuke, et al.
Publicado: (2016)

Corrigendum: Afatinib for Advanced Non-small Cell Lung Cancer in a Case With an Uncommon Epidermal Growth Factor Receptor Mutation (G719A) Identified in the Cerebrospinal Fluid
por: Ma, Chunhua, et al.
Publicado: (2019)

Effective Treatment With Afatinib of Lung Adenocarcinoma With Leptomeningeal Metastasis Harboring the Exon 18 p.G719A Mutation in the EGFR Gene Was Detected in Cerebrospinal Fluid: A Case Report
por: Ma, Chunhua, et al.
Publicado: (2020)

EGFR (p. G719A+L747V)/EML4-ALK Co-alterations in Lung Adenocarcinoma with Leptomeningeal Metastasis Responding to Afatinib Treatment: A Case Report
por: Lu, Zhiqin, et al.
Publicado: (2021)

Late and Rapid Relapse in Mediastinum from Testicular Germ Cell Tumor Stage I Over 13 Years after Surgery
por: Fukushima, Toshirou, et al.
Publicado: (2019)

A case of mediastinal mesenchymal tumor with pericytic neoplasm feature that responded to radiation therapy
por: Muramoto, Miho, et al.
Publicado: (2023)

Mechanisms of acquired resistance to afatinib clarified with liquid biopsy
por: Nakamura, Tomomi, et al.
Publicado: (2018)

Primary mediastinal dedifferentiated liposarcoma resected by lateral thoracotomy with video-assisted thoracoscopic surgery
por: Hamanaka, Kazutoshi, et al.
Publicado: (2016)

Laparoscopic Resection of an Undifferentiated Pleomorphic Splenic Sarcoma
por: Hashmi, Asra, et al.
Publicado: (2010)

Correction to Lancet Oncol 2017; 18: 719–31
Publicado: (2017)

SUN-719 The Impact of FOXA3 on Testicular Steroidogenesis
por: Kim, Hansle, et al.
Publicado: (2020)

The extent of pulmonary resection for lung metastases from colorectal cancer
por: Mishima, Shuji, et al.
Publicado: (2022)

719. The Respiratory Pathogen Panel and Antibiotic Utilization in the Emergency Department
por: Taupin, Daniel, et al.
Publicado: (2018)

MON-719 The Cellular and Molecular Landscape of Hypothalamic Patterning and Differentiation
por: Kim, Thomas
Publicado: (2020)

Osimertinib Treatment Was Unsuccessful for Lung Adenocarcinoma with G719S, S768I, and T790M Mutations
por: Nasu, Shingo, et al.
Publicado: (2018)

Clinical Significance of Various Drug-Sensitivity Markers in Patients with Surgically Resected Pulmonary Pleomorphic Carcinoma
por: Imai, Hisao, et al.
Publicado: (2019)

Observational Study of Sequential Afatinib and Osimertinib in EGFR Mutation-Positive NSCLC: Patients Treated with a 40-mg Starting Dose of Afatinib
por: Yamamoto, Nobuyuki, et al.
Publicado: (2019)

Afatinib in Untreated Stage IIIB/IV Lung Adenocarcinoma with Major Uncommon Epidermal Growth Factor Receptor (EGFR) Mutations (G719X/L861Q/S768I): A Multicenter Observational Study in Taiwan
por: Hsu, Ping-Chih, et al.
Publicado: (2023)

Impact of counterclockwise rotation of the right middle lobe following right upper lobectomy
por: Koike, Sachie, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_h7nu85tl6v5grvuvustm1ej6t2