Repeat Intravitreal Dexamethasone Implant for Refractory Cystoid Macular Edema in Syphilitic Uveitis

PURPOSE: To report the successful utilization of adjunctive repeat intravitreal corticosteroid therapy for the treatment of cystoid macular edema in syphilis-related uveitis. METHODS/PATIENTS: An HIV-positive patient with treated ocular syphilis who developed refractory cystoid macular edema (CME) w...

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Autores principales: Lautredou, Cassandra C., Hardin, Joshua S., Chancellor, John R., Uwaydat, Sami H., Ellabban, Abdallah A., Sallam, Ahmed B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836310/
https://www.ncbi.nlm.nih.gov/pubmed/29670789
http://dx.doi.org/10.1155/2018/7419823
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author Lautredou, Cassandra C.
Hardin, Joshua S.
Chancellor, John R.
Uwaydat, Sami H.
Ellabban, Abdallah A.
Sallam, Ahmed B.
author_facet Lautredou, Cassandra C.
Hardin, Joshua S.
Chancellor, John R.
Uwaydat, Sami H.
Ellabban, Abdallah A.
Sallam, Ahmed B.
author_sort Lautredou, Cassandra C.
collection PubMed
description PURPOSE: To report the successful utilization of adjunctive repeat intravitreal corticosteroid therapy for the treatment of cystoid macular edema in syphilis-related uveitis. METHODS/PATIENTS: An HIV-positive patient with treated ocular syphilis who developed refractory cystoid macular edema (CME) was treated with repeat intravitreal corticosteroid therapy including dexamethasone intravitreal implants. RESULTS: Treatment led to the resolution of CME and improvement in visual acuity. CONCLUSIONS: Intravitreal corticosteroid therapy may be a viable adjunctive treatment for refractory CME in patients with treated syphilitic uveitis. Corticosteroid-induced exacerbation of infection is unlikely in patients with an adequate serologic treatment response.
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spelling pubmed-58363102018-04-18 Repeat Intravitreal Dexamethasone Implant for Refractory Cystoid Macular Edema in Syphilitic Uveitis Lautredou, Cassandra C. Hardin, Joshua S. Chancellor, John R. Uwaydat, Sami H. Ellabban, Abdallah A. Sallam, Ahmed B. Case Rep Ophthalmol Med Case Report PURPOSE: To report the successful utilization of adjunctive repeat intravitreal corticosteroid therapy for the treatment of cystoid macular edema in syphilis-related uveitis. METHODS/PATIENTS: An HIV-positive patient with treated ocular syphilis who developed refractory cystoid macular edema (CME) was treated with repeat intravitreal corticosteroid therapy including dexamethasone intravitreal implants. RESULTS: Treatment led to the resolution of CME and improvement in visual acuity. CONCLUSIONS: Intravitreal corticosteroid therapy may be a viable adjunctive treatment for refractory CME in patients with treated syphilitic uveitis. Corticosteroid-induced exacerbation of infection is unlikely in patients with an adequate serologic treatment response. Hindawi 2018-02-19 /pmc/articles/PMC5836310/ /pubmed/29670789 http://dx.doi.org/10.1155/2018/7419823 Text en Copyright © 2018 Cassandra C. Lautredou et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lautredou, Cassandra C.
Hardin, Joshua S.
Chancellor, John R.
Uwaydat, Sami H.
Ellabban, Abdallah A.
Sallam, Ahmed B.
Repeat Intravitreal Dexamethasone Implant for Refractory Cystoid Macular Edema in Syphilitic Uveitis
title Repeat Intravitreal Dexamethasone Implant for Refractory Cystoid Macular Edema in Syphilitic Uveitis
title_full Repeat Intravitreal Dexamethasone Implant for Refractory Cystoid Macular Edema in Syphilitic Uveitis
title_fullStr Repeat Intravitreal Dexamethasone Implant for Refractory Cystoid Macular Edema in Syphilitic Uveitis
title_full_unstemmed Repeat Intravitreal Dexamethasone Implant for Refractory Cystoid Macular Edema in Syphilitic Uveitis
title_short Repeat Intravitreal Dexamethasone Implant for Refractory Cystoid Macular Edema in Syphilitic Uveitis
title_sort repeat intravitreal dexamethasone implant for refractory cystoid macular edema in syphilitic uveitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836310/
https://www.ncbi.nlm.nih.gov/pubmed/29670789
http://dx.doi.org/10.1155/2018/7419823
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