Intravenous injection of beta-amyloid seeds promotes cerebral amyloid angiopathy (CAA)

Seeding and spread of beta-amyloid (Aβ) pathologies have been considered to be based on prion-like mechanisms. However, limited transmissibility of Aβ seeding activity upon peripheral exposure would represent a key difference to prions, not only in terms of pathogenesis but also in terms of potentia...

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Detalles Bibliográficos
Autores principales: Burwinkel, Michael, Lutzenberger, Manuel, Heppner, Frank L., Schulz-Schaeffer, Walter, Baier, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836327/
https://www.ncbi.nlm.nih.gov/pubmed/29506560
http://dx.doi.org/10.1186/s40478-018-0511-7

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