Detection of Proteome Diversity Resulted from Alternative Splicing is Limited by Trypsin Cleavage Specificity

Alternative splicing dramatically increases transcriptome complexity but its contribution to proteome diversity remains controversial. Exon-exon junction spanning peptides provide direct evidence for the translation of specific splice isoforms and are critical for delineating protein isoform complex...

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Detalles Bibliográficos
Autores principales: Wang, Xiaojing, Codreanu, Simona G., Wen, Bo, Li, Kai, Chambers, Matthew C., Liebler, Daniel C., Zhang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836368/
https://www.ncbi.nlm.nih.gov/pubmed/29222161
http://dx.doi.org/10.1074/mcp.RA117.000155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836368/
https://www.ncbi.nlm.nih.gov/pubmed/29222161
http://dx.doi.org/10.1074/mcp.RA117.000155

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