Cargando…
Pridopidine: Overview of Pharmacology and Rationale for its Use in Huntington’s Disease
Despite advances in understanding the pathophysiology of Huntington’s disease (HD), there are currently no effective pharmacological agents available to treat core symptoms or to stop or prevent the progression of this hereditary neurodegenerative disorder. Pridopidine, a novel small molecule compou...
Autores principales: | Waters, Susanna, Tedroff, Joakim, Ponten, Henrik, Klamer, Daniel, Sonesson, Clas, Waters, Nicholas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836399/ https://www.ncbi.nlm.nih.gov/pubmed/29480206 http://dx.doi.org/10.3233/JHD-170267 |
Ejemplares similares
-
A first‐in‐human oral dose study of mesdopetam (IRL790) to assess its safety, tolerability, and pharmacokinetics in healthy male volunteers
por: Sjöberg, Folke, et al.
Publicado: (2021) -
Profile of pridopidine and its potential in the treatment of Huntington disease: the evidence to date
por: Squitieri, Ferdinando, et al.
Publicado: (2015) -
Pridopidine activates neuroprotective pathways impaired in Huntington Disease
por: Geva, Michal, et al.
Publicado: (2016) -
Metoprolol‐pridopidine drug–drug interaction and food effect assessments of pridopidine, a new drug for treatment of Huntington's disease
por: Rabinovich‐Guilatt, Laura, et al.
Publicado: (2017) -
Altered pattern of brain dopamine synthesis in male adolescents with attention deficit hyperactivity disorder
por: Forssberg, Hans, et al.
Publicado: (2006)