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Differences in Synaptic Dysfunction Between rTg4510 and APP/PS1 Mouse Models of Alzheimer’s Disease

Genetically modified mice have provided insights into the progression and pathology of Alzheimer’s disease (AD). Here, we have examined two mouse models of AD: the rTg4510 mouse, which overexpresses mutant human Tau gene, and the APP/PS1 mouse, which overexpresses mutant human genes for amyloid prec...

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Detalles Bibliográficos
Autores principales:	Gelman, Simon, Palma, Jonathan, Tombaugh, Geoffrey, Ghavami, Afshin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836403/ https://www.ncbi.nlm.nih.gov/pubmed/29154272 http://dx.doi.org/10.3233/JAD-170457

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