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miR-221-5p enhances cell proliferation and metastasis through post-transcriptional regulation of SOCS1 in human prostate cancer

BACKGROUND: To investigate the effect of miR-221-5p on cell proliferaton and metastasis of human prostate cancer in vitro and vivo. METHODS: We established PC3 cell lines with stable overexpression or silencing of miRNA-221-5p via lentivirus infection. miRNA-221-5p and its target gene SOCS1 expressi...

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Detalles Bibliográficos
Autores principales:	Shao, Ning, Ma, Gui, Zhang, Jinying, Zhu, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836432/ https://www.ncbi.nlm.nih.gov/pubmed/29506516 http://dx.doi.org/10.1186/s12894-018-0325-8

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