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DNA methylation holds prognostic information in relapsed precursor B-cell acute lymphoblastic leukemia
BACKGROUND: Few biological markers are associated with survival after relapse of B-cell precursor acute lymphoblastic leukemia (BCP-ALL). In pediatric T-cell ALL, we have identified promoter-associated methylation alterations that correlate with prognosis. Here, the prognostic relevance of CpG islan...
Autores principales: | Borssén, Magnus, Nordlund, Jessica, Haider, Zahra, Landfors, Mattias, Larsson, Pär, Kanerva, Jukka, Schmiegelow, Kjeld, Flaegstad, Trond, Jónsson, Ólafur Gísli, Frost, Britt-Marie, Palle, Josefine, Forestier, Erik, Heyman, Mats, Hultdin, Magnus, Lönnerholm, Gudmar, Degerman, Sofie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836434/ https://www.ncbi.nlm.nih.gov/pubmed/29515676 http://dx.doi.org/10.1186/s13148-018-0466-3 |
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