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AKT1 restricts the invasive capacity of head and neck carcinoma cells harboring a constitutively active PI3 kinase activity

BACKGROUND: In mammals, the AKT/PKB protein kinase family comprises three members (AKT1–3). PI3-Kinase (PI3K), a key oncogene involved in a wide variety of cancers, drives AKT activity. Constitutive activation of the PI3K/AKT pathway has been associated with tumorigenic properties including uncontro...

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Detalles Bibliográficos
Autores principales:	Brolih, Sanja, Parks, Scott K., Vial, Valérie, Durivault, Jérôme, Mostosi, Livio, Pouysségur, Jacques, Pagès, Gilles, Picco, Vincent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836445/ https://www.ncbi.nlm.nih.gov/pubmed/29506489 http://dx.doi.org/10.1186/s12885-018-4169-0

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