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HIV Activates the Tyrosine Kinase Hck to Secrete ADAM Protease-Containing Extracellular Vesicles

HIV-Nef activates the myeloid cell-typical tyrosine kinase Hck, but its molecular role in the viral life cycle is not entirely understood. We found that HIV plasma extracellular vesicles (HIV pEV) containing/10 proteases and Nef also harbor Hck, and analyzed its role in the context of HIV pEV secret...

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Detalles Bibliográficos
Autores principales:	Lee, J.-H., Ostalecki, C., Zhao, Z., Kesti, T., Bruns, H., Simon, B., Harrer, T., Saksela, K., Baur, A.S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836510/ https://www.ncbi.nlm.nih.gov/pubmed/29331674 http://dx.doi.org/10.1016/j.ebiom.2018.01.004

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