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Differential Role of Cathepsins S and B In Hepatic APC-Mediated NKT Cell Activation and Cytokine Secretion
Natural killer T (NKT) cells exhibit a specific tissue distribution, displaying the liver the highest NKT/conventional T cell ratio. Upon antigen stimulation, NKT cells secrete Th1 cytokines, including interferon γ (IFNγ), and Th2 cytokines, including IL-4 that recruit and activate other innate immu...
Autores principales: | de Mingo Pulido, Álvaro, de Gregorio, Estefanía, Chandra, Shilpi, Colell, Anna, Morales, Albert, Kronenberg, Mitchell, Marí, Montserrat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836516/ https://www.ncbi.nlm.nih.gov/pubmed/29541077 http://dx.doi.org/10.3389/fimmu.2018.00391 |
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