pKWmEB: integration of Kruskal–Wallis test with empirical Bayes under polygenic background control for multi-locus genome-wide association study

Although nonparametric methods in genome-wide association studies (GWAS) are robust in quantitative trait nucleotide (QTN) detection, the absence of polygenic background control in single-marker association in genome-wide scans results in a high false positive rate. To overcome this issue, we propos...

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Detalles Bibliográficos
Autores principales: Ren, Wen-Long, Wen, Yang-Jun, Dunwell, Jim M., Zhang, Yuan-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836593/
https://www.ncbi.nlm.nih.gov/pubmed/29234158
http://dx.doi.org/10.1038/s41437-017-0007-4

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