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Coordination of FOXA2 and SIRT6 suppresses the hepatocellular carcinoma progression through ZEB2 inhibition
BACKGROUND: The Forkhead transcription family member FOXA2 plays a fundamental role in hepatocellular carcinoma (HCC) progression, but the precise interaction factor and molecular regulation of FOXA2 are not fully understood. OBJECTIVE: In this study, we found that FOXA2 could interact with sirtuin...
Autores principales: | Liu, Jinghua, Yu, Zhen, Xiao, Yuanyuan, Meng, Qiong, Wang, Yeying, Chang, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836661/ https://www.ncbi.nlm.nih.gov/pubmed/29535552 http://dx.doi.org/10.2147/CMAR.S150552 |
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