Progranulin deficiency leads to prolonged persistence of macrophages, accompanied with myofiber hypertrophy in regenerating muscle

Skeletal muscle has an ability to regenerate in response to injury due to the presence of satellite cells. Injury in skeletal muscle causes infiltration of pro-inflammatory macrophages (M1 macrophages) to remove necrotic myofibers, followed by their differentiation into anti-inflammatory macrophages...

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Detalles Bibliográficos
Autores principales: SUGIHARA, Hidetoshi, MIYAJI, Kei, YAMANOUCHI, Keitaro, MATSUWAKI, Takashi, NISHIHARA, Masugi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2017
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836776/
https://www.ncbi.nlm.nih.gov/pubmed/29249750
http://dx.doi.org/10.1292/jvms.17-0638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836776/
https://www.ncbi.nlm.nih.gov/pubmed/29249750
http://dx.doi.org/10.1292/jvms.17-0638

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