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Sitagliptin and Roux‐en‐Y gastric bypass modulate insulin secretion via regulation of intra‐islet PYY

AIMS: The gut hormone peptide tyrosine tyrosine (PYY) is critical for maintaining islet integrity and restoring islet function following Roux‐en‐Y gastric bypass (RYGB). The expression of PYY and its receptors (NPYRs) in islets has been documented but not fully characterized. Modulation of islet PYY...

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Detalles Bibliográficos
Autores principales: Guida, Claudia, McCulloch, Laura J., Godazgar, Mahdieh, Stephen, Sam D., Baker, Charlotte, Basco, Davide, Dong, Jiawen, Chen, Duan, Clark, Anne, Ramracheya, Reshma D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836881/
https://www.ncbi.nlm.nih.gov/pubmed/28892258
http://dx.doi.org/10.1111/dom.13113

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