Pharmacokinetics of concentrated naloxone nasal spray for opioid overdose reversal: Phase I healthy volunteer study

BACKGROUND AND AIMS: Take‐home naloxone can prevent death from heroin/opioid overdose, but pre‐provision is difficult because naloxone is usually given by injection. Non‐injectable alternatives, including naloxone nasal sprays, are currently being developed. To be effective, the intranasal (i.n.) sp...

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Detalles Bibliográficos
Autores principales: McDonald, Rebecca, Lorch, Ulrike, Woodward, Jo, Bosse, Björn, Dooner, Helen, Mundin, Gill, Smith, Kevin, Strang, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836974/
https://www.ncbi.nlm.nih.gov/pubmed/29143400
http://dx.doi.org/10.1111/add.14033

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