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The cryo-electron microscopy structure of huntingtin

Huntingtin (Htt) is a large (348 kDa) protein, essential for embryonic development and involved in diverse cellular activities such as vesicular transport, endocytosis, autophagy and transcription regulation1,2. While an integrative understanding of Htt's biological functions is lacking, the la...

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Detalles Bibliográficos
Autores principales:	Guo, Qiang, Huang, Bin, Cheng, Jingdong, Seefelder, Manuel, Engler, Tatjana, Pfeifer, Günter, Oeckl, Patrick, Otto, Markus, Moser, Franziska, Maurer, Melanie, Pautsch, Alexander, Baumeister, Wolfgang, Fernández-Busnadiego, Rubén, Kochanek, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837020/ https://www.ncbi.nlm.nih.gov/pubmed/29466333 http://dx.doi.org/10.1038/nature25502

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