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The technical reliability and biotemporal stability of cerebrospinal fluid biomarkers for profiling multiple pathophysiologies in Alzheimer’s disease

OBJECTIVE: Alzheimer’s disease (AD) is a complex neurodegenerative disease driven by multiple interacting pathophysiological processes that ultimately results in synaptic loss, neuronal death, and dementia. We implemented a fit-for-purpose modeled approach to qualify a broad selection of commerciall...

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Detalles Bibliográficos
Autores principales:	Trombetta, Bianca A., Carlyle, Becky C., Koenig, Aaron M., Shaw, Leslie M., Trojanowski, John Q., Wolk, David A., Locascio, Joseph J., Arnold, Steven E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837100/ https://www.ncbi.nlm.nih.gov/pubmed/29505610 http://dx.doi.org/10.1371/journal.pone.0193707

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