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Targeting IL-2: an unexpected effect in treating immunological diseases

Regulatory T cells (Treg) play a crucial role in maintaining immune homeostasis since Treg dysfunction in both animals and humans is associated with multi-organ autoimmune and inflammatory disease. While IL-2 is generally considered to promote T-cell proliferation and enhance effector T-cell functio...

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Detalles Bibliográficos
Autores principales: Ye, Congxiu, Brand, David, Zheng, Song G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837126/
https://www.ncbi.nlm.nih.gov/pubmed/29527328
http://dx.doi.org/10.1038/s41392-017-0002-5