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Propionibacterium acnes induces intervertebral disc degeneration by promoting nucleus pulposus cell apoptosis via the TLR2/JNK/mitochondrial-mediated pathway

Evidence suggests that intervertebral disc degeneration (IVDD) can be induced by Propionibacterium acnes (P. acnes), although the underlying mechanisms are unclear. In this study, we analyzed the pathological changes in degenerated human intervertebral discs (IVDs) infected with P. acnes. Compared w...

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Detalles Bibliográficos
Autores principales:	Lin, Yazhou, Jiao, Yucheng, Yuan, Ye, Zhou, Zezhu, Zheng, Yuehuan, Xiao, Jiaqi, Li, Changwei, Chen, Zhe, Cao, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837142/ https://www.ncbi.nlm.nih.gov/pubmed/29323102 http://dx.doi.org/10.1038/s41426-017-0002-0

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