Enterovirus D68 virus-like particles expressed in Pichia pastoris potently induce neutralizing antibody responses and confer protection against lethal viral infection in mice

Enterovirus D68 (EV-D68) has been increasingly associated with severe respiratory illness and neurological complications in children worldwide. However, no vaccine is currently available to prevent EV-D68 infection. In the present study, we investigated the possibility of developing a virus-like par...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Zhang, Xueyang, Zhang, Wei, Dai, Wenlong, Xie, Jing, Ye, Liping, Wang, Hongli, Chen, Huan, Liu, Qingwei, Gong, Sitang, Geng, Lanlan, Huang, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837163/
https://www.ncbi.nlm.nih.gov/pubmed/29323105
http://dx.doi.org/10.1038/s41426-017-0005-x

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