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Randomized multicentre pilot study of sacubitril/valsartan versus irbesartan in patients with chronic kidney disease: United Kingdom Heart and Renal Protection (HARP)- III—rationale, trial design and baseline data
BACKGROUND: Patients with chronic kidney disease (CKD) are at risk of progression to end-stage renal disease and cardiovascular disease. Data from other populations and animal experiments suggest that neprilysin inhibition (which augments the natriuretic peptide system) may reduce these risks, but c...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837485/ https://www.ncbi.nlm.nih.gov/pubmed/27646835 http://dx.doi.org/10.1093/ndt/gfw321 |