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Minocycline reduces chronic microglial activation after brain trauma but increases neurodegeneration
Survivors of a traumatic brain injury can deteriorate years later, developing brain atrophy and dementia. Traumatic brain injury triggers chronic microglial activation, but it is unclear whether this is harmful or beneficial. A successful chronic-phase treatment for traumatic brain injury might be t...
Autores principales: | Scott, Gregory, Zetterberg, Henrik, Jolly, Amy, Cole, James H, De Simoni, Sara, Jenkins, Peter O, Feeney, Claire, Owen, David R, Lingford-Hughes, Anne, Howes, Oliver, Patel, Maneesh C, Goldstone, Anthony P, Gunn, Roger N, Blennow, Kaj, Matthews, Paul M, Sharp, David J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837493/ https://www.ncbi.nlm.nih.gov/pubmed/29272357 http://dx.doi.org/10.1093/brain/awx339 |
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