HDL-cholesterol levels and risk of age-related macular degeneration: a multiethnic genetic study using Mendelian randomization

BACKGROUND: Dyslipidemia, particularly high-density lipoprotein cholesterol (HDL-C), has recently been implicated in the pathogenesis of age-related macular degeneration (AMD), the leading cause of vision loss. However, epidemiological studies have yielded conflicting results. METHODS: We investigat...

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Detalles Bibliográficos
Autores principales: Fan, Qiao, Maranville, Joseph C, Fritsche, Lars, Sim, Xueling, Cheung, Chui Ming Gemmy, Chen, Li Jia, Gorski, Mathias, Yamashiro, Kenji, Ahn, Jeeyun, Laude, Augustinus, Dorajoo, Rajkumar, Lim, Tock Han, Teo, Yik-Ying, Blaustein, Robert O, Yoshimura, Nagahisa, Park, Kyu-Hyung, Pang, Chi Pui, Tai, E Shyong, Khor, Chiea Chuen, Wong, Tien Yin, Runz, Heiko, Cheng, Ching-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Vision
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837540/
https://www.ncbi.nlm.nih.gov/pubmed/29025108
http://dx.doi.org/10.1093/ije/dyx189

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