Serine is the major residue for ADP-ribosylation upon DNA damage

Poly(ADP-ribose) polymerases (PARPs) are a family of enzymes that synthesise ADP-ribosylation (ADPr), a reversible modification of proteins that regulates many different cellular processes. Several mammalian PARPs are known to regulate the DNA damage response, but it is not clear which amino acids i...

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Detalles Bibliográficos
Autores principales: Palazzo, Luca, Leidecker, Orsolya, Prokhorova, Evgeniia, Dauben, Helen, Matic, Ivan, Ahel, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837557/
https://www.ncbi.nlm.nih.gov/pubmed/29480802
http://dx.doi.org/10.7554/eLife.34334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837557/
https://www.ncbi.nlm.nih.gov/pubmed/29480802
http://dx.doi.org/10.7554/eLife.34334

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