Cargando…

Editor’s Highlight: Pregnancy Alters Aflatoxin B(1) Metabolism and Increases DNA Damage in Mouse Liver

Pregnancy is a complex physiological state, in which the metabolism of endogenous as well as exogenous agents is ostensibly altered. One exogenous agent of concern is the hepatocarcinogen aflatoxin B(1) (AFB(1)), a foodborne fungal toxin, that requires phase I metabolic oxidation for conversion to i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sriwattanapong, Kanokwan, Slocum, Stephen L., Chawanthayatham, Supawadee, Fedeles, Bogdan I., Egner, Patricia A., Groopman, John D., Satayavivad, Jutamaad, Croy, Robert G., Essigmann, John M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Increased Aflatoxin B1 Damage in Pregnant Mice
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837592/ https://www.ncbi.nlm.nih.gov/pubmed/28973694 http://dx.doi.org/10.1093/toxsci/kfx171

Ejemplares similares

Early detection of the aflatoxin B(1) mutational fingerprint: A diagnostic tool for liver cancer
por: Fedeles, Bogdan I., et al.
Publicado: (2017)

Molecular origins of mutational spectra produced by the environmental carcinogen N-nitrosodimethylamine and S(N)1 chemotherapeutic agents
por: Armijo, Amanda L, et al.
Publicado: (2023)

Assessment of radiation damage behaviour in a large collection of empirically optimized datasets highlights the importance of unmeasured complicating effects
por: Krojer, Tobias, et al.
Publicado: (2011)

Non-rigid image registration to reduce beam-induced blurring of cryo-electron microscopy images
por: Karimi Nejadasl, Fatemeh, et al.
Publicado: (2013)

Radiation damage to nucleoprotein complexes in macromolecular crystallography
por: Bury, Charles, et al.
Publicado: (2015)

Colouring cryo-cooled crystals: online microspectrophotometry
por: McGeehan, John, et al.
Publicado: (2009)

Correlated single-crystal electronic absorption spectroscopy and X-ray crystallography at NSLS beamline X26-C
por: Orville, Allen M., et al.
Publicado: (2011)

Radiation damage in room-temperature data acquisition with the PILATUS 6M pixel detector
por: Rajendran, Chitra, et al.
Publicado: (2011)

A beginner’s guide to radiation damage
por: Holton, James M.
Publicado: (2009)

Determination of X-ray flux using silicon pin diodes
por: Owen, Robin L., et al.
Publicado: (2009)

A new on-axis multimode spectrometer for the macromolecular crystallography beamlines of the Swiss Light Source
por: Owen, Robin L., et al.
Publicado: (2009)

Experimental procedure for the characterization of radiation damage in macromolecular crystals
por: Leal, Ricardo M. F., et al.
Publicado: (2011)

Additional phase information from UV damage of selenomethionine labelled proteins
por: de Sanctis, Daniele, et al.
Publicado: (2011)

Macromolecular crystallography radiation damage research: what’s new?
por: Garman, Elspeth F., et al.
Publicado: (2011)

Revealing low-dose radiation damage using single-crystal spectroscopy
por: Owen, Robin L., et al.
Publicado: (2011)

Radiation damage in single-particle cryo-electron microscopy: effects of dose and dose rate
por: Karuppasamy, Manikandan, et al.
Publicado: (2011)

To scavenge or not to scavenge, that is STILL the question
por: Allan, Elizabeth G., et al.
Publicado: (2013)

A survey of global radiation damage to 15 different protein crystal types at room temperature: a new decay model
por: Leal, Ricardo Miguel Ferraz, et al.
Publicado: (2013)

Identifying and quantifying radiation damage at the atomic level
por: Gerstel, Markus, et al.
Publicado: (2015)

XFEL diffraction: developing processing methods to optimize data quality
por: Sauter, Nicholas K.
Publicado: (2015)

OH cleavage from tyrosine: debunking a myth
por: Bury, Charles S., et al.
Publicado: (2017)

Identification of the point of diminishing returns in high-multiplicity data collection for sulfur SAD phasing
por: Storm, Selina L. S., et al.
Publicado: (2017)

Development of a dose-limiting data collection strategy for serial synchrotron rotation crystallography
por: Hasegawa, Kazuya, et al.
Publicado: (2017)

Development of tools to automate quantitative analysis of radiation damage in SAXS experiments
por: Brooks-Bartlett, Jonathan C., et al.
Publicado: (2017)

Conformational variation of proteins at room temperature is not dominated by radiation damage
por: Russi, Silvia, et al.
Publicado: (2017)

Bragg coherent diffraction imaging and metrics for radiation damage in protein micro-crystallography
por: Coughlan, H. D., et al.
Publicado: (2017)

Direct measurement of X-ray-induced heating of microcrystals
por: Warren, Anna J., et al.
Publicado: (2019)

Low-dose X-ray structure analysis of cytochrome c oxidase utilizing high-energy X-rays
por: Ueno, Go, et al.
Publicado: (2019)

Modified Cornell electrocardiographic criteria in the assessment of left ventricular hypertrophy geometry of patients with essential hypertension
por: Xu, Min, et al.
Publicado: (2020)

Diagnosis of chronic stage of hypertensive retinopathy based on spectral domain optical coherence tomography
por: Feng, Xue, et al.
Publicado: (2020)

Single-particle cryo-EM: alternative schemes to improve dose efficiency
por: Zhang, Yue, et al.
Publicado: (2021)

Radiation damage to biological samples: still a pertinent issue
por: Garman, Elspeth F., et al.
Publicado: (2021)

Guidelines for de novo phasing using multiple small-wedge data collection
por: Baba, Seiki, et al.
Publicado: (2021)

Hydroxyl radical mediated damage of proteins in low oxygen solution investigated using X-ray footprinting mass spectrometry
por: Kristensen, Line G., et al.
Publicado: (2021)

A SAXS-based approach to rationally evaluate radical scavengers – toward eliminating radiation damage in solution and crystallographic studies
por: Stachowski, Timothy R., et al.
Publicado: (2021)

Ultrafast dynamics and scattering of protic ionic liquids induced by XFEL pulses
por: Patra, Kajwal Kumar, et al.
Publicado: (2021)

Role of tautomerism in RNA biochemistry
por: Singh, Vipender, et al.
Publicado: (2015)

Integrative In Silico and In Vitro Transcriptomics Analysis Revealed Gene Expression Changes and Oncogenic Features of Normal Cholangiocytes after Chronic Alcohol Exposure
por: Chujan, Suthipong, et al.
Publicado: (2019)

Identification of Potential Molecular Mechanisms and Prognostic Markers for Oral Squamous Cell Carcinoma: A Bioinformatics Analysis
por: Chujan, Suthipong, et al.
Publicado: (2023)

Preterm Birth Associated With Group B Streptococcus Maternal Colonization Worldwide: Systematic Review and Meta-analyses
por: Bianchi-Jassir, Fiorella, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_i8qgsemuihdct1f1ivrmij2gai