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Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption

BACKGROUND: Mendelian randomization (MR) is being increasingly used to strengthen causal inference in observational studies. Availability of summary data of genetic associations for a variety of phenotypes from large genome-wide association studies (GWAS) allows straightforward application of MR usi...

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Detalles Bibliográficos
Autores principales:	Hartwig, Fernando Pires, Davey Smith, George, Bowden, Jack
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Methods
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837715/ https://www.ncbi.nlm.nih.gov/pubmed/29040600 http://dx.doi.org/10.1093/ije/dyx102

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