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Deleterious effects of phosphate on vascular and endothelial function via disruption to the nitric oxide pathway
BACKGROUND: Hyperphosphataemia is an independent risk factor for accelerated cardiovascular disease in chronic kidney disease (CKD), although the mechanism for this is poorly understood. We investigated the effects of sustained exposure to a high-phosphate environment on endothelial function in cell...
Autores principales: | Stevens, Kathryn K, Denby, Laura, Patel, Rajan K, Mark, Patrick B, Kettlewell, Sarah, Smith, Godfrey L, Clancy, Marc J, Delles, Christian, Jardine, Alan G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837731/ https://www.ncbi.nlm.nih.gov/pubmed/27448672 http://dx.doi.org/10.1093/ndt/gfw252 |
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