A novel but frequent variant in LPA KIV-2 is associated with a pronounced Lp(a) and cardiovascular risk reduction

AIMS: Lp(a) concentrations represent a major cardiovascular risk factor and are almost entirely controlled by one single locus (LPA). However, many genetic factors in LPA governing the enormous variance of Lp(a) levels are still unknown. Since up to 70% of the LPA coding sequence are located in a di...

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Detalles Bibliográficos
Autores principales: Coassin, Stefan, Erhart, Gertraud, Weissensteiner, Hansi, Eca Guimarães de Araújo, Mariana, Lamina, Claudia, Schönherr, Sebastian, Forer, Lukas, Haun, Margot, Losso, Jamie Lee, Köttgen, Anna, Schmidt, Konrad, Utermann, Gerd, Peters, Annette, Gieger, Christian, Strauch, Konstantin, Finkenstedt, Armin, Bale, Reto, Zoller, Heinz, Paulweber, Bernhard, Eckardt, Kai-Uwe, Hüttenhofer, Alexander, Huber, Lukas A., Kronenberg, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Fast Track Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837733/
https://www.ncbi.nlm.nih.gov/pubmed/28444229
http://dx.doi.org/10.1093/eurheartj/ehx174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837733/
https://www.ncbi.nlm.nih.gov/pubmed/28444229
http://dx.doi.org/10.1093/eurheartj/ehx174

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