Cargando…

Hyperactivation of nuclear receptor coactivators induces PERK-dependent cell death

Nuclear receptor coactivators (NCOAs) function as coactivators for nuclear receptors as well as several other transcription factors and potentiate their transcriptional activity. NCOAs play an important role in biology of hormone-dependent and -independent cancers. MCB-613 is a recently described, s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hossain, Muhammad Mosaraf, Barua, David, Arabkari, Vahid, Islam, Nahidul, Gupta, Ananya, Gupta, Sanjeev
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837751/ https://www.ncbi.nlm.nih.gov/pubmed/29545931 http://dx.doi.org/10.18632/oncotarget.24451

Ejemplares similares

PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response
por: Gupta, Ananya, et al.
Publicado: (2015)

UPR-Induced miR-616 Inhibits Human Breast Cancer Cell Growth and Migration by Targeting c-MYC
por: Arabkari, Vahid, et al.
Publicado: (2023)

RRM2 and CDC6 are novel effectors of XBP1-mediated endocrine resistance and predictive markers of tamoxifen sensitivity
por: Barua, David, et al.
Publicado: (2023)

NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK–eIF2α–ATF4 signalling in breast cancer
por: Gupta, A, et al.
Publicado: (2016)

Downregulation of miR-17-92 Cluster by PERK Fine-Tunes Unfolded Protein Response Mediated Apoptosis
por: Read, Danielle E., et al.
Publicado: (2021)

Hic-5, an adaptor-like nuclear receptor coactivator
por: Heitzer, Marjet D., et al.
Publicado: (2006)

Nuclear Receptor Coactivators (NCOAs) and Corepressors (NCORs) in the Brain
por: Sun, Zheng, et al.
Publicado: (2020)

Regulation of Hepatic Gluconeogenesis by Nuclear Receptor Coactivator 6
por: Oh, Gyun-Sik, et al.
Publicado: (2022)

PNRC is a unique nuclear receptor coactivator that stimulates RNA polymerase III-dependent transcription
por: Zhou, Dujin, et al.
Publicado: (2007)

Essential roles for the nuclear receptor coactivator Ncoa3 in pluripotency
por: Percharde, Michelle, et al.
Publicado: (2013)

XBP1 increases transactivation of somatic mutants of ESR1 and loss of XBP1 reverses endocrine resistance conferred by gain-of-function Y537S ESR1 mutation
por: Barua, David, et al.
Publicado: (2020)

Nuclear role for human Argonaute-1 as an estrogen-dependent transcription coactivator
por: Gómez Acuña, Luciana I., et al.
Publicado: (2020)

Identification and Characterization of the Alternatively Spliced Nuclear Receptor Coactivator-6 Isoforms
por: Li, Qingtian, et al.
Publicado: (2011)

The oncogenic roles of nuclear receptor coactivator 1 in human esophageal carcinoma
por: Wang, Lu, et al.
Publicado: (2018)

NMDA receptor-mediated excitotoxicity depends on the coactivation of synaptic and extrasynaptic receptors
por: Zhou, X, et al.
Publicado: (2013)

A scoring system for the follow up study of nuclear receptor coactivator complexes
por: Han, Sang Jun, et al.
Publicado: (2006)

Diverse coactivator recruitment through differential PPARγ nuclear receptor agonism
por: Lizcano, Fernando, et al.
Publicado: (2013)

Expression of Nuclear Receptor Coactivators in the Human Fetal Membranes at Term before and after Labor
por: Ou, Che-Wei Ryan, et al.
Publicado: (2012)

Corepressive function of nuclear receptor coactivator 2 in androgen receptor of prostate cancer cells treated with antiandrogen
por: Takeda, Keisuke, et al.
Publicado: (2016)

Ciclopirox activates PERK-dependent endoplasmic reticulum stress to drive cell death in colorectal cancer
por: Qi, Jianjun, et al.
Publicado: (2020)

Steroid receptor coactivators – their role in immunity
por: Gilad, Yosi, et al.
Publicado: (2022)

Steroid Receptor Coactivator 3 Regulates Synaptic Plasticity and Hippocampus-dependent Memory
por: Zhang, Hai-Long, et al.
Publicado: (2021)

SRC-3 Has a Role in Cancer Other Than as a Nuclear Receptor Coactivator
por: Ma, Gang, et al.
Publicado: (2011)

Nuclear pyruvate kinase M2 complex serves as a transcriptional coactivator of arylhydrocarbon receptor
por: Matsuda, Shun, et al.
Publicado: (2016)

Expression and function of nuclear receptor coactivator 4 isoforms in transformed endometriotic and malignant ovarian cells
por: Rockfield, Stephanie, et al.
Publicado: (2017)

Identification of a nuclear receptor/coactivator developmental signaling pathway in the nematode parasite Strongyloides stercoralis
por: Cheong, Mi Cheong, et al.
Publicado: (2021)

Mitochondrial Fusion Is Increased by the Nuclear Coactivator PGC-1β
por: Liesa, Marc, et al.
Publicado: (2008)

Correction: Ciclopirox activates PERK-dependent endoplasmic reticulum stress to drive cell death in colorectal cancer
por: Qi, Jianjun, et al.
Publicado: (2020)

Transcriptional Coactivators: Driving Force of Plant Immunity
por: Khan, Muhammad Saad Shoaib, et al.
Publicado: (2022)

Glycosylation PERKs
por: Williams, Ruth
Publicado: (2007)

Cell Cycle-Dependent Expression of Dub3, Nanog and the p160 Family of Nuclear Receptor Coactivators (NCoAs) in Mouse Embryonic Stem Cells
por: van der Laan, Siem, et al.
Publicado: (2014)

Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis
por: Gupta, S, et al.
Publicado: (2012)

PRIC295, a Nuclear Receptor Coactivator, Identified from PPARα-Interacting Cofactor Complex
por: Pyper, Sean R., et al.
Publicado: (2010)

Cyclin E as a Coactivator of the Androgen Receptor
por: Yamamoto, Ayako, et al.
Publicado: (2000)

Biochemical Identification of a Nuclear Coactivator Protein Required for AtrR-Dependent Gene Regulation in Aspergillus fumigatus
por: Paul, Sanjoy, et al.
Publicado: (2022)

Hyperactivated endolysosomal trafficking in melanoma
por: Alonso-Curbelo, Direna, et al.
Publicado: (2015)

Non-autonomous consequences of cell death and other perks of being metazoan
por: Su, Tin Tin
Publicado: (2015)

TNF-dependent hyperactivation of RIPK1-dependent cytotoxic signaling during embryogenesis and inflammation
por: Mocarski, Edward S., et al.
Publicado: (2021)

The dynamic properties of a nuclear coactivator binding domain are evolutionarily conserved
por: Karlsson, Elin, et al.
Publicado: (2022)

Correction: Cell Cycle-Dependent Expression of Dub3, Nanog and the p160 Family of Nuclear Receptor Coactivators (NCoAs) in Mouse Embryonic Stem Cells
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_a9qmnjofcg8aql9k7f26cvld4n