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Profound deficits in hippocampal synaptic plasticity after traumatic brain injury and seizure is ameliorated by prophylactic levetiracetam
AIM: To determine the precise effects of post-traumatic seizure activity on hippocampal processes, we induced seizures at various intervals after traumatic brain injury (TBI) and analyzed plasticity at CA1 Schaffer collateral synapses. MATERIAL AND METHODS: Rats were initially separated into two gro...
Autores principales: | Chen, Yuan-Hao, Kuo, Tung-Tai, Yi-Kung Huang, Eagle, Hoffer, Barry J., Chou, Yu-Ching, Chiang, Yung-Hsiao, Ma, Hsin-I, Miller, Jonathan P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837755/ https://www.ncbi.nlm.nih.gov/pubmed/29545916 http://dx.doi.org/10.18632/oncotarget.23923 |
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