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Periostin blockade overcomes chemoresistance via restricting the expansion of mesenchymal tumor subpopulations in breast cancer
Recent studies suggest a functional involvement of Epithelial-Mesenchymal Transition (EMT) in tumor chemoresistance. Specifically, EMT is associated with chemoresistance and poor prognosis in triple-negative breast cancer. However, no effective therapy targeting EMT has been developed. Here, we repo...
Autores principales: | Nakazawa, Youya, Taniyama, Yoshiaki, Sanada, Fumihiro, Morishita, Ryuichi, Nakamori, Shoji, Morimoto, Koji, Yeung, Kay T., Yang, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838092/ https://www.ncbi.nlm.nih.gov/pubmed/29507310 http://dx.doi.org/10.1038/s41598-018-22340-7 |
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