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Eosinophilic gastroenteritis; a report of two cases with different presentations

Eosinophilic gastroenteritis is a rare inflammatory disease, defined by infiltration of eosinophils in gastrointestinal (GI) tract, but the etiology of this disorder is unknown. Depends on the involvement region of Eosinophilic gastroenteritis, GI symptoms are variable including abdominal pain, mala...

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Autores principales: Sadeghi, Amir, Abdi, Elham, Jamshidfar, Negin, Barzegar, Farnoush, Lahmi, Farhad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838196/
https://www.ncbi.nlm.nih.gov/pubmed/29511487
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author Sadeghi, Amir
Abdi, Elham
Jamshidfar, Negin
Barzegar, Farnoush
Lahmi, Farhad
author_facet Sadeghi, Amir
Abdi, Elham
Jamshidfar, Negin
Barzegar, Farnoush
Lahmi, Farhad
author_sort Sadeghi, Amir
collection PubMed
description Eosinophilic gastroenteritis is a rare inflammatory disease, defined by infiltration of eosinophils in gastrointestinal (GI) tract, but the etiology of this disorder is unknown. Depends on the involvement region of Eosinophilic gastroenteritis, GI symptoms are variable including abdominal pain, malabsorption, gastric and duodenal ulcer. Due to its non-specific symptoms, the diagnosis is based on upper GI endoscopy followed by histopathological examination of the biopsies, which shows eosinophilic infiltration in different layers of GI tract. In this article we report two cases with gastrointestinal disorders. The first case was a 52-year-old man with a history of peripheral edema over the past 3 months and low level of serum albumin. All the necessary evaluations were done and increase number of eosinophils were found in duodenal biopsies. The second case was a 42-year-old man presented with a history of chronic diarrhea over the past two years. Main causes of diarrhea were ruled out and small intestine biopsies confirmed submucosal eosinophilic infiltration. Therefore, corticosteroid therapy was administered for both patients then they were followed for a year. During this time all of the symptoms were disappeared and they did not recur in the first year of follow up.
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spelling pubmed-58381962018-03-06 Eosinophilic gastroenteritis; a report of two cases with different presentations Sadeghi, Amir Abdi, Elham Jamshidfar, Negin Barzegar, Farnoush Lahmi, Farhad Gastroenterol Hepatol Bed Bench Case Presentation Eosinophilic gastroenteritis is a rare inflammatory disease, defined by infiltration of eosinophils in gastrointestinal (GI) tract, but the etiology of this disorder is unknown. Depends on the involvement region of Eosinophilic gastroenteritis, GI symptoms are variable including abdominal pain, malabsorption, gastric and duodenal ulcer. Due to its non-specific symptoms, the diagnosis is based on upper GI endoscopy followed by histopathological examination of the biopsies, which shows eosinophilic infiltration in different layers of GI tract. In this article we report two cases with gastrointestinal disorders. The first case was a 52-year-old man with a history of peripheral edema over the past 3 months and low level of serum albumin. All the necessary evaluations were done and increase number of eosinophils were found in duodenal biopsies. The second case was a 42-year-old man presented with a history of chronic diarrhea over the past two years. Main causes of diarrhea were ruled out and small intestine biopsies confirmed submucosal eosinophilic infiltration. Therefore, corticosteroid therapy was administered for both patients then they were followed for a year. During this time all of the symptoms were disappeared and they did not recur in the first year of follow up. Shaheed Beheshti University of Medical Sciences 2017 /pmc/articles/PMC5838196/ /pubmed/29511487 Text en ©2017 RIGLD, Research Institute for Gastroenterology and Liver Diseases This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Presentation
Sadeghi, Amir
Abdi, Elham
Jamshidfar, Negin
Barzegar, Farnoush
Lahmi, Farhad
Eosinophilic gastroenteritis; a report of two cases with different presentations
title Eosinophilic gastroenteritis; a report of two cases with different presentations
title_full Eosinophilic gastroenteritis; a report of two cases with different presentations
title_fullStr Eosinophilic gastroenteritis; a report of two cases with different presentations
title_full_unstemmed Eosinophilic gastroenteritis; a report of two cases with different presentations
title_short Eosinophilic gastroenteritis; a report of two cases with different presentations
title_sort eosinophilic gastroenteritis; a report of two cases with different presentations
topic Case Presentation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838196/
https://www.ncbi.nlm.nih.gov/pubmed/29511487
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