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Eosinophilic gastroenteritis; a report of two cases with different presentations
Eosinophilic gastroenteritis is a rare inflammatory disease, defined by infiltration of eosinophils in gastrointestinal (GI) tract, but the etiology of this disorder is unknown. Depends on the involvement region of Eosinophilic gastroenteritis, GI symptoms are variable including abdominal pain, mala...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shaheed Beheshti University of Medical Sciences
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838196/ https://www.ncbi.nlm.nih.gov/pubmed/29511487 |
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author | Sadeghi, Amir Abdi, Elham Jamshidfar, Negin Barzegar, Farnoush Lahmi, Farhad |
author_facet | Sadeghi, Amir Abdi, Elham Jamshidfar, Negin Barzegar, Farnoush Lahmi, Farhad |
author_sort | Sadeghi, Amir |
collection | PubMed |
description | Eosinophilic gastroenteritis is a rare inflammatory disease, defined by infiltration of eosinophils in gastrointestinal (GI) tract, but the etiology of this disorder is unknown. Depends on the involvement region of Eosinophilic gastroenteritis, GI symptoms are variable including abdominal pain, malabsorption, gastric and duodenal ulcer. Due to its non-specific symptoms, the diagnosis is based on upper GI endoscopy followed by histopathological examination of the biopsies, which shows eosinophilic infiltration in different layers of GI tract. In this article we report two cases with gastrointestinal disorders. The first case was a 52-year-old man with a history of peripheral edema over the past 3 months and low level of serum albumin. All the necessary evaluations were done and increase number of eosinophils were found in duodenal biopsies. The second case was a 42-year-old man presented with a history of chronic diarrhea over the past two years. Main causes of diarrhea were ruled out and small intestine biopsies confirmed submucosal eosinophilic infiltration. Therefore, corticosteroid therapy was administered for both patients then they were followed for a year. During this time all of the symptoms were disappeared and they did not recur in the first year of follow up. |
format | Online Article Text |
id | pubmed-5838196 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Shaheed Beheshti University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-58381962018-03-06 Eosinophilic gastroenteritis; a report of two cases with different presentations Sadeghi, Amir Abdi, Elham Jamshidfar, Negin Barzegar, Farnoush Lahmi, Farhad Gastroenterol Hepatol Bed Bench Case Presentation Eosinophilic gastroenteritis is a rare inflammatory disease, defined by infiltration of eosinophils in gastrointestinal (GI) tract, but the etiology of this disorder is unknown. Depends on the involvement region of Eosinophilic gastroenteritis, GI symptoms are variable including abdominal pain, malabsorption, gastric and duodenal ulcer. Due to its non-specific symptoms, the diagnosis is based on upper GI endoscopy followed by histopathological examination of the biopsies, which shows eosinophilic infiltration in different layers of GI tract. In this article we report two cases with gastrointestinal disorders. The first case was a 52-year-old man with a history of peripheral edema over the past 3 months and low level of serum albumin. All the necessary evaluations were done and increase number of eosinophils were found in duodenal biopsies. The second case was a 42-year-old man presented with a history of chronic diarrhea over the past two years. Main causes of diarrhea were ruled out and small intestine biopsies confirmed submucosal eosinophilic infiltration. Therefore, corticosteroid therapy was administered for both patients then they were followed for a year. During this time all of the symptoms were disappeared and they did not recur in the first year of follow up. Shaheed Beheshti University of Medical Sciences 2017 /pmc/articles/PMC5838196/ /pubmed/29511487 Text en ©2017 RIGLD, Research Institute for Gastroenterology and Liver Diseases This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Presentation Sadeghi, Amir Abdi, Elham Jamshidfar, Negin Barzegar, Farnoush Lahmi, Farhad Eosinophilic gastroenteritis; a report of two cases with different presentations |
title | Eosinophilic gastroenteritis; a report of two cases with different presentations |
title_full | Eosinophilic gastroenteritis; a report of two cases with different presentations |
title_fullStr | Eosinophilic gastroenteritis; a report of two cases with different presentations |
title_full_unstemmed | Eosinophilic gastroenteritis; a report of two cases with different presentations |
title_short | Eosinophilic gastroenteritis; a report of two cases with different presentations |
title_sort | eosinophilic gastroenteritis; a report of two cases with different presentations |
topic | Case Presentation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838196/ https://www.ncbi.nlm.nih.gov/pubmed/29511487 |
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