Direct conversion of injury-site myeloid cells to fibroblast-like cells of granulation tissue

Inflammation, following injury, induces cellular plasticity as an inherent component of physiological tissue repair. The dominant fate of wound macrophages is unclear and debated. Here we show that two-thirds of all granulation tissue fibroblasts, otherwise known to be of mesenchymal origin, are der...

Descripción completa

Detalles Bibliográficos
Autores principales: Sinha, Mithun, Sen, Chandan K., Singh, Kanhaiya, Das, Amitava, Ghatak, Subhadip, Rhea, Brian, Blackstone, Britani, Powell, Heather M., Khanna, Savita, Roy, Sashwati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838200/
https://www.ncbi.nlm.nih.gov/pubmed/29507336
http://dx.doi.org/10.1038/s41467-018-03208-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838200/
https://www.ncbi.nlm.nih.gov/pubmed/29507336
http://dx.doi.org/10.1038/s41467-018-03208-w

Ejemplares similares