Life times of metastable states guide regulatory signaling in transcriptional riboswitches

Transcriptional riboswitches modulate downstream gene expression by a tight coupling of ligand-dependent RNA folding kinetics with the rate of transcription. RNA folding pathways leading to functional ON and OFF regulation involve the formation of metastable states within well-defined sequence inter...

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Detalles Bibliográficos
Autores principales: Helmling, Christina, Klötzner, Dean-Paulos, Sochor, Florian, Mooney, Rachel Anne, Wacker, Anna, Landick, Robert, Fürtig, Boris, Heckel, Alexander, Schwalbe, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838219/
https://www.ncbi.nlm.nih.gov/pubmed/29507289
http://dx.doi.org/10.1038/s41467-018-03375-w

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