Allogeneic dendritic cells stimulated with antibodies against HLA class II polarize naive T cells in a follicular helper phenotype

Follicular helper T cells (Tfh) are crucial for the production of high-affinity antibodies, such as alloantibodies, by providing the signals for B-cell proliferation and differentiation. Here, we demonstrate that human allogeneic dendritic cells (DC) stimulated with antibodies against HLA class II a...

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Detalles Bibliográficos
Autores principales: Désy, Olivier, Béland, Stéphanie, Vallin, Patrice, Riopel, Julie, Latulippe, Eva, Wagner, Eric, De Serres, Sacha A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838222/
https://www.ncbi.nlm.nih.gov/pubmed/29507364
http://dx.doi.org/10.1038/s41598-018-22391-w

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