Cargando…

Mechanical complications and outcomes following invasive emergency procedures in severely injured trauma patients

This study aimes to determine the complication rates, possible risk factors and outcomes of emergency procedures performed during resuscitation of severely injured patients. The medical records of patients with an injury severity score (ISS) >15 admitted to the University Hospital Leipzig from 20...

Descripción completa

Detalles Bibliográficos
Autores principales: Struck, Manuel F., Fakler, Johannes K. M., Bernhard, Michael, Busch, Thilo, Stumpp, Patrick, Hempel, Gunther, Beilicke, André, Stehr, Sebastian N., Josten, Christoph, Wrigge, Hermann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838247/
https://www.ncbi.nlm.nih.gov/pubmed/29507415
http://dx.doi.org/10.1038/s41598-018-22457-9
_version_ 1783304220015853568
author Struck, Manuel F.
Fakler, Johannes K. M.
Bernhard, Michael
Busch, Thilo
Stumpp, Patrick
Hempel, Gunther
Beilicke, André
Stehr, Sebastian N.
Josten, Christoph
Wrigge, Hermann
author_facet Struck, Manuel F.
Fakler, Johannes K. M.
Bernhard, Michael
Busch, Thilo
Stumpp, Patrick
Hempel, Gunther
Beilicke, André
Stehr, Sebastian N.
Josten, Christoph
Wrigge, Hermann
author_sort Struck, Manuel F.
collection PubMed
description This study aimes to determine the complication rates, possible risk factors and outcomes of emergency procedures performed during resuscitation of severely injured patients. The medical records of patients with an injury severity score (ISS) >15 admitted to the University Hospital Leipzig from 2010 to 2015 were reviewed. Within the first 24 hours of treatment, 526 patients had an overall mechanical complication rate of 26.2%. Multivariate analysis revealed out-of-hospital airway management (OR 3.140; 95% CI 1.963–5.023; p < 0.001) and ISS (per ISS point: OR 1.024; 95% CI 1.003–1.045; p = 0.027) as independent predictors of any mechanical complications. Airway management complications (13.2%) and central venous catheter complications (11.4%) were associated with ISS >32.5 (p < 0.001) and ISS >33.5 (p = 0.005), respectively. Chest tube complications (15.8%) were associated with out-of-hospital insertion (p = 0.002) and out-of-hospital tracheal intubation (p = 0.033). Arterial line complications (9.4%) were associated with admission serum lactate >4.95 mmol/L (p = 0.001) and base excess <−4.05 mmol/L (p = 0.008). In multivariate analysis, complications were associated with an increased length of stay in the intensive care unit (p = 0.019) but not with 24 hour mortality (p = 0.930). Increasing injury severity may contribute to higher complexity of the individual emergency treatment and is thus associated with higher mechanical complication rates providing potential for further harm.
format Online
Article
Text
id pubmed-5838247
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-58382472018-03-12 Mechanical complications and outcomes following invasive emergency procedures in severely injured trauma patients Struck, Manuel F. Fakler, Johannes K. M. Bernhard, Michael Busch, Thilo Stumpp, Patrick Hempel, Gunther Beilicke, André Stehr, Sebastian N. Josten, Christoph Wrigge, Hermann Sci Rep Article This study aimes to determine the complication rates, possible risk factors and outcomes of emergency procedures performed during resuscitation of severely injured patients. The medical records of patients with an injury severity score (ISS) >15 admitted to the University Hospital Leipzig from 2010 to 2015 were reviewed. Within the first 24 hours of treatment, 526 patients had an overall mechanical complication rate of 26.2%. Multivariate analysis revealed out-of-hospital airway management (OR 3.140; 95% CI 1.963–5.023; p < 0.001) and ISS (per ISS point: OR 1.024; 95% CI 1.003–1.045; p = 0.027) as independent predictors of any mechanical complications. Airway management complications (13.2%) and central venous catheter complications (11.4%) were associated with ISS >32.5 (p < 0.001) and ISS >33.5 (p = 0.005), respectively. Chest tube complications (15.8%) were associated with out-of-hospital insertion (p = 0.002) and out-of-hospital tracheal intubation (p = 0.033). Arterial line complications (9.4%) were associated with admission serum lactate >4.95 mmol/L (p = 0.001) and base excess <−4.05 mmol/L (p = 0.008). In multivariate analysis, complications were associated with an increased length of stay in the intensive care unit (p = 0.019) but not with 24 hour mortality (p = 0.930). Increasing injury severity may contribute to higher complexity of the individual emergency treatment and is thus associated with higher mechanical complication rates providing potential for further harm. Nature Publishing Group UK 2018-03-05 /pmc/articles/PMC5838247/ /pubmed/29507415 http://dx.doi.org/10.1038/s41598-018-22457-9 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Struck, Manuel F.
Fakler, Johannes K. M.
Bernhard, Michael
Busch, Thilo
Stumpp, Patrick
Hempel, Gunther
Beilicke, André
Stehr, Sebastian N.
Josten, Christoph
Wrigge, Hermann
Mechanical complications and outcomes following invasive emergency procedures in severely injured trauma patients
title Mechanical complications and outcomes following invasive emergency procedures in severely injured trauma patients
title_full Mechanical complications and outcomes following invasive emergency procedures in severely injured trauma patients
title_fullStr Mechanical complications and outcomes following invasive emergency procedures in severely injured trauma patients
title_full_unstemmed Mechanical complications and outcomes following invasive emergency procedures in severely injured trauma patients
title_short Mechanical complications and outcomes following invasive emergency procedures in severely injured trauma patients
title_sort mechanical complications and outcomes following invasive emergency procedures in severely injured trauma patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838247/
https://www.ncbi.nlm.nih.gov/pubmed/29507415
http://dx.doi.org/10.1038/s41598-018-22457-9
work_keys_str_mv AT struckmanuelf mechanicalcomplicationsandoutcomesfollowinginvasiveemergencyproceduresinseverelyinjuredtraumapatients
AT faklerjohanneskm mechanicalcomplicationsandoutcomesfollowinginvasiveemergencyproceduresinseverelyinjuredtraumapatients
AT bernhardmichael mechanicalcomplicationsandoutcomesfollowinginvasiveemergencyproceduresinseverelyinjuredtraumapatients
AT buschthilo mechanicalcomplicationsandoutcomesfollowinginvasiveemergencyproceduresinseverelyinjuredtraumapatients
AT stumpppatrick mechanicalcomplicationsandoutcomesfollowinginvasiveemergencyproceduresinseverelyinjuredtraumapatients
AT hempelgunther mechanicalcomplicationsandoutcomesfollowinginvasiveemergencyproceduresinseverelyinjuredtraumapatients
AT beilickeandre mechanicalcomplicationsandoutcomesfollowinginvasiveemergencyproceduresinseverelyinjuredtraumapatients
AT stehrsebastiann mechanicalcomplicationsandoutcomesfollowinginvasiveemergencyproceduresinseverelyinjuredtraumapatients
AT jostenchristoph mechanicalcomplicationsandoutcomesfollowinginvasiveemergencyproceduresinseverelyinjuredtraumapatients
AT wriggehermann mechanicalcomplicationsandoutcomesfollowinginvasiveemergencyproceduresinseverelyinjuredtraumapatients