Severe pancytopenia and splenomegaly associated with felty's syndrome, both fully responsive solely to corticosteroids

In severe cases of pancytopenia with subsequent infections due to long‐term untreated Felty's syndrome, the initiation of immunosuppressive treatment with sole prednisone (1 mg/kg iv) should be considered, despite that, the low neutrocytes count would make one physician hesitant. A full resolut...

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Autores principales: Liatsos, George D., Tsironi, Ioanna, Vassilopoulos, Dimitrios, Dourakis, Spyridon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838277/
https://www.ncbi.nlm.nih.gov/pubmed/29531729
http://dx.doi.org/10.1002/ccr3.1396
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author Liatsos, George D.
Tsironi, Ioanna
Vassilopoulos, Dimitrios
Dourakis, Spyridon
author_facet Liatsos, George D.
Tsironi, Ioanna
Vassilopoulos, Dimitrios
Dourakis, Spyridon
author_sort Liatsos, George D.
collection PubMed
description In severe cases of pancytopenia with subsequent infections due to long‐term untreated Felty's syndrome, the initiation of immunosuppressive treatment with sole prednisone (1 mg/kg iv) should be considered, despite that, the low neutrocytes count would make one physician hesitant. A full resolution of whole blood count within 3 weeks and a 30% reduction in spleens sized was noted.
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spelling pubmed-58382772018-03-12 Severe pancytopenia and splenomegaly associated with felty's syndrome, both fully responsive solely to corticosteroids Liatsos, George D. Tsironi, Ioanna Vassilopoulos, Dimitrios Dourakis, Spyridon Clin Case Rep Case Reports In severe cases of pancytopenia with subsequent infections due to long‐term untreated Felty's syndrome, the initiation of immunosuppressive treatment with sole prednisone (1 mg/kg iv) should be considered, despite that, the low neutrocytes count would make one physician hesitant. A full resolution of whole blood count within 3 weeks and a 30% reduction in spleens sized was noted. John Wiley and Sons Inc. 2018-01-31 /pmc/articles/PMC5838277/ /pubmed/29531729 http://dx.doi.org/10.1002/ccr3.1396 Text en © 2018 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Liatsos, George D.
Tsironi, Ioanna
Vassilopoulos, Dimitrios
Dourakis, Spyridon
Severe pancytopenia and splenomegaly associated with felty's syndrome, both fully responsive solely to corticosteroids
title Severe pancytopenia and splenomegaly associated with felty's syndrome, both fully responsive solely to corticosteroids
title_full Severe pancytopenia and splenomegaly associated with felty's syndrome, both fully responsive solely to corticosteroids
title_fullStr Severe pancytopenia and splenomegaly associated with felty's syndrome, both fully responsive solely to corticosteroids
title_full_unstemmed Severe pancytopenia and splenomegaly associated with felty's syndrome, both fully responsive solely to corticosteroids
title_short Severe pancytopenia and splenomegaly associated with felty's syndrome, both fully responsive solely to corticosteroids
title_sort severe pancytopenia and splenomegaly associated with felty's syndrome, both fully responsive solely to corticosteroids
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838277/
https://www.ncbi.nlm.nih.gov/pubmed/29531729
http://dx.doi.org/10.1002/ccr3.1396
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