Cargando…

RON tyrosine kinase mutations in brain metastases from lung cancer

RON mutations might identify actionable targets in highly aggressive lung tumours http://ow.ly/RTUp30hSBX6

Detalles Bibliográficos
Autores principales:	Milan, Melissa, Benvenuti, Silvia, Balderacchi, Alice Maria, Virzì, Anna Rita, Gentile, Alessandra, Senetta, Rebecca, Cassoni, Paola, Comoglio, Paolo Maria, Stella, Giulia Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	European Respiratory Society 2018
Materias:	Original Research Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838354/ https://www.ncbi.nlm.nih.gov/pubmed/29531956 http://dx.doi.org/10.1183/23120541.00083-2017

Ejemplares similares

Erratum to: Ockham’s razor for the MET-driven invasive growth linking idiopathic pulmonary fibrosis and cancer
por: Stella, Giulia M., et al.
Publicado: (2017)

Reviving oncogenic addiction to MET bypassed by BRAF (G469A) mutation
por: Virzì, Anna Rita, et al.
Publicado: (2018)

Autoinhibition of the Ron receptor tyrosine kinase by the juxtamembrane domain
por: Wang, Xin, et al.
Publicado: (2014)

An Introduction and Overview of RON Receptor Tyrosine Kinase Signaling
por: Hunt, Brian G., et al.
Publicado: (2023)

Regulation of Macrophage Polarization by RON Receptor Tyrosine Kinase Signaling
por: Chaudhuri, Amitabha
Publicado: (2014)

Cancers of unknown primary origin: current perspectives and future therapeutic strategies
por: Stella, Giulia Maria, et al.
Publicado: (2012)

MET Activation and Physical Dynamics of the Metastatic Process: The Paradigm of Cancers of Unknown Primary Origin
por: Stella, Giulia M., et al.
Publicado: (2017)

Significance of the entire C-terminus in biological activities mediated by the RON receptor tyrosine kinase and its oncogenic variant RON160
por: Lu, Yi, et al.
Publicado: (2008)

The Receptor Tyrosine Kinase RON and Its Isoforms as Therapeutic Targets in Ewing Sarcoma
por: Berning, Philipp, et al.
Publicado: (2020)

Cancer of Unknown Primary (CUP): genetic evidence for a novel nosological entity? A case report
por: Benvenuti, Silvia, et al.
Publicado: (2020)

Variant RONΔ160 of the RON receptor tyrosine kinase promotes the growth and invasion in vitro and in vivo in gastric cancer cell lines
por: Zhou, Dong-Hui, et al.
Publicado: (2015)

Evidence for 2-Methoxyestradiol-Mediated Inhibition of Receptor Tyrosine Kinase RON in the Management of Prostate Cancer
por: Batth, Izhar Singh, et al.
Publicado: (2021)

Crystal Structure of the Sema-PSI Extracellular Domain of Human RON Receptor Tyrosine Kinase
por: Chao, Kinlin L., et al.
Publicado: (2012)

The MST1R/RON Tyrosine Kinase in Cancer: Oncogenic Functions and Therapeutic Strategies
por: Cazes, Alex, et al.
Publicado: (2022)

Role of PAX8 in the regulation of MET and RON receptor tyrosine kinases in non-small cell lung cancer
por: Kanteti, Rajani, et al.
Publicado: (2014)

THE RON RECEPTOR TYROSINE KINASE POSITIVELY REGULATES ANGIOGENIC CHEMOKINE PRODUCTION IN PROSTATE CANCER CELLS
por: Thobe, Megan N., et al.
Publicado: (2009)

MicroRNA Expression Profiling of Lung Cancer with Differential Expression of the RON Receptor Tyrosine Kinase
por: Ou, Huilin, et al.
Publicado: (2021)

Caveolin-1 as a promoter of tumour spreading: when, how, where and why
por: Senetta, Rebecca, et al.
Publicado: (2013)

The RON receptor tyrosine kinase promotes MSP-independent cell spreading and survival in breast epithelial cells
por: Feres, K.J., et al.
Publicado: (2008)

Expression of the RON receptor tyrosine kinase and its association with gastric carcinoma versus normal gastric tissues
por: Zhou, Donghui, et al.
Publicado: (2008)

Pathogenesis of RON receptor tyrosine kinase in cancer cells: activation mechanism, functional crosstalk, and signaling addiction
por: Wang, Ming-Hai, et al.
Publicado: (2013)

Neuroprotective Role of the Ron Receptor Tyrosine Kinase Underlying Central Nervous System Inflammation in Health and Disease
por: Dey, Adwitia, et al.
Publicado: (2018)

The RON Receptor Tyrosine Kinase Promotes Metastasis by Triggering MBD4-Dependent DNA Methylation Reprogramming
por: Cunha, Stéphanie, et al.
Publicado: (2014)

Ockham’s razor for the MET-driven invasive growth linking idiopathic pulmonary fibrosis and cancer
por: Stella, Giulia M., et al.
Publicado: (2016)

Ron tyrosine kinase receptor synergises with EGFR to confer adverse features in head and neck squamous cell carcinoma
por: Keller, J, et al.
Publicado: (2013)

A novel protein isoform of the RON tyrosine kinase receptor transforms human pancreatic duct epithelial cells
por: Chakedis, Jeffery, et al.
Publicado: (2015)

OPN promotes the aggressiveness of non-small-cell lung cancer cells through the activation of the RON tyrosine kinase
por: Hao, Chengcheng, et al.
Publicado: (2019)

Splice variants of the extracellular region of RON receptor tyrosine kinase in lung cancer cell lines identified by PCR and sequencing
por: Krishnaswamy, Soundararajan, et al.
Publicado: (2017)

MET and RON receptor tyrosine kinases in colorectal adenocarcinoma: molecular features as drug targets and antibody-drug conjugates for therapy
por: Yao, Hang-Ping, et al.
Publicado: (2020)

Androgen receptor status predicts development of brain metastases in ovarian cancers
por: Mittica, Gloria, et al.
Publicado: (2017)

ROR1 is a pseudokinase that is crucial for MET-driven tumorigenesis
por: Lazzari, Luca, et al.
Publicado: (2013)

Deletion or insertion in the first immunoglobulin-plexin-transcription (IPT) domain differentially regulates expression and tumorigenic activities of RON receptor Tyrosine Kinase
por: Ma, Qi, et al.
Publicado: (2010)

Targeting RON receptor tyrosine kinase for treatment of advanced solid cancers: antibody–drug conjugates as lead drug candidates for clinical trials
por: Yao, Hang-Ping, et al.
Publicado: (2020)

Ron Knockdown and Ron Monoclonal Antibody IMC-RON8 Sensitize Pancreatic Cancer to Histone Deacetylase Inhibitors (HDACi)
por: Zou, Yi, et al.
Publicado: (2013)

CAVEOLIN-1 expression in brain metastasis from lung cancer predicts worse outcome and radioresistance, irrespective of tumor histotype
por: Duregon, Eleonora, et al.
Publicado: (2015)

Transformation and scattering activities of the receptor tyrosine kinase RON/Stk in rodent fibroblasts and lack of regulation by the jaagsiekte sheep retrovirus receptor, Hyal2
por: Miller, A Dusty, et al.
Publicado: (2004)

RON and MET Co-overexpression Are Significant Pathological Characteristics of Poor Survival and Therapeutic Targets of Tyrosine Kinase Inhibitors in Triple-Negative Breast Cancer
por: Weng, Tian-Hao, et al.
Publicado: (2020)

Aberrant RON and MET Co-overexpression as Novel Prognostic Biomarkers of Shortened Patient Survival and Therapeutic Targets of Tyrosine Kinase Inhibitors in Pancreatic Cancer
por: Hu, Chen-Yu, et al.
Publicado: (2019)

Bulevar del ron
por: Pécheral, Jacques R. (Jacques Renaud), 1908-
Publicado: (1966)

Bulevar del ron
por: Pécheral, Jacques, 1908-
Publicado: (1972)

Cannot write session to /tmp/vufind_sessions/sess_dqt3td5cb97acojhp5ra509mt6