Cover Feature: Organometallic Nucleosides: Synthesis and Biological Evaluation of Substituted Dicobalt Hexacarbonyl 2′‐Deoxy‐5‐oxopropynyluridines (ChemistryOpen 3/2018)

The Cover Feature focuses on the crystal structure of dicobalt‐hexacarbonyl‐modified 5‐alkynyl‐2′‐deoxyuridine, which was investigated for in vitro antiproliferative activity against human cancer cells. The formation of reactive oxygen species in K562 cells implicates the involvement of oxidative st...

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Autores principales: Kaczmarek, Renata, Korczyński, Dariusz, Królewska‐Golińska, Karolina, Wheeler, Kraig A., Chavez, Ferman A., Mikus, Agnieszka, Dembinski, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Cover Pictures
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838386/
http://dx.doi.org/10.1002/open.201800018
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author Kaczmarek, Renata
Korczyński, Dariusz
Królewska‐Golińska, Karolina
Wheeler, Kraig A.
Chavez, Ferman A.
Mikus, Agnieszka
Dembinski, Roman
author_facet Kaczmarek, Renata
Korczyński, Dariusz
Królewska‐Golińska, Karolina
Wheeler, Kraig A.
Chavez, Ferman A.
Mikus, Agnieszka
Dembinski, Roman
author_sort Kaczmarek, Renata
collection PubMed
description The Cover Feature focuses on the crystal structure of dicobalt‐hexacarbonyl‐modified 5‐alkynyl‐2′‐deoxyuridine, which was investigated for in vitro antiproliferative activity against human cancer cells. The formation of reactive oxygen species in K562 cells implicates the involvement of oxidative stress in the mode of action. Cover art by Samantha McCarthy. More information can be found in the Full Paper by R. Kaczmarek, R. Dembinski, et al. on page 237 in Issue 3, 2018 (DOI: 10.1002/open.201700168).[Image: see text]
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spelling pubmed-58383862018-03-12 Cover Feature: Organometallic Nucleosides: Synthesis and Biological Evaluation of Substituted Dicobalt Hexacarbonyl 2′‐Deoxy‐5‐oxopropynyluridines (ChemistryOpen 3/2018) Kaczmarek, Renata Korczyński, Dariusz Królewska‐Golińska, Karolina Wheeler, Kraig A. Chavez, Ferman A. Mikus, Agnieszka Dembinski, Roman ChemistryOpen Cover Pictures The Cover Feature focuses on the crystal structure of dicobalt‐hexacarbonyl‐modified 5‐alkynyl‐2′‐deoxyuridine, which was investigated for in vitro antiproliferative activity against human cancer cells. The formation of reactive oxygen species in K562 cells implicates the involvement of oxidative stress in the mode of action. Cover art by Samantha McCarthy. More information can be found in the Full Paper by R. Kaczmarek, R. Dembinski, et al. on page 237 in Issue 3, 2018 (DOI: 10.1002/open.201700168).[Image: see text] John Wiley and Sons Inc. 2018-02-12 /pmc/articles/PMC5838386/ http://dx.doi.org/10.1002/open.201800018 Text en © 2018 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim
spellingShingle Cover Pictures
Kaczmarek, Renata
Korczyński, Dariusz
Królewska‐Golińska, Karolina
Wheeler, Kraig A.
Chavez, Ferman A.
Mikus, Agnieszka
Dembinski, Roman
Cover Feature: Organometallic Nucleosides: Synthesis and Biological Evaluation of Substituted Dicobalt Hexacarbonyl 2′‐Deoxy‐5‐oxopropynyluridines (ChemistryOpen 3/2018)
title Cover Feature: Organometallic Nucleosides: Synthesis and Biological Evaluation of Substituted Dicobalt Hexacarbonyl 2′‐Deoxy‐5‐oxopropynyluridines (ChemistryOpen 3/2018)
title_full Cover Feature: Organometallic Nucleosides: Synthesis and Biological Evaluation of Substituted Dicobalt Hexacarbonyl 2′‐Deoxy‐5‐oxopropynyluridines (ChemistryOpen 3/2018)
title_fullStr Cover Feature: Organometallic Nucleosides: Synthesis and Biological Evaluation of Substituted Dicobalt Hexacarbonyl 2′‐Deoxy‐5‐oxopropynyluridines (ChemistryOpen 3/2018)
title_full_unstemmed Cover Feature: Organometallic Nucleosides: Synthesis and Biological Evaluation of Substituted Dicobalt Hexacarbonyl 2′‐Deoxy‐5‐oxopropynyluridines (ChemistryOpen 3/2018)
title_short Cover Feature: Organometallic Nucleosides: Synthesis and Biological Evaluation of Substituted Dicobalt Hexacarbonyl 2′‐Deoxy‐5‐oxopropynyluridines (ChemistryOpen 3/2018)
title_sort cover feature: organometallic nucleosides: synthesis and biological evaluation of substituted dicobalt hexacarbonyl 2′‐deoxy‐5‐oxopropynyluridines (chemistryopen 3/2018)
topic Cover Pictures
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838386/
http://dx.doi.org/10.1002/open.201800018
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