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Management of bacterial infection in the liver transplant candidate

Bacterial infection (BI) is a common cause of impairment of liver function in patients with cirrhosis, especially in the liver transplant candidates. These patients share an immunocompromised state and increased susceptibility to develop community and hospital-acquired infections. The changing epide...

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Autores principales: Ferrarese, Alberto, Zanetto, Alberto, Becchetti, Chiara, Sciarrone, Salvatore Stefano, Shalaby, Sarah, Germani, Giacomo, Gambato, Martina, Russo, Francesco Paolo, Burra, Patrizia, Senzolo, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838441/
https://www.ncbi.nlm.nih.gov/pubmed/29527258
http://dx.doi.org/10.4254/wjh.v10.i2.222
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author Ferrarese, Alberto
Zanetto, Alberto
Becchetti, Chiara
Sciarrone, Salvatore Stefano
Shalaby, Sarah
Germani, Giacomo
Gambato, Martina
Russo, Francesco Paolo
Burra, Patrizia
Senzolo, Marco
author_facet Ferrarese, Alberto
Zanetto, Alberto
Becchetti, Chiara
Sciarrone, Salvatore Stefano
Shalaby, Sarah
Germani, Giacomo
Gambato, Martina
Russo, Francesco Paolo
Burra, Patrizia
Senzolo, Marco
author_sort Ferrarese, Alberto
collection PubMed
description Bacterial infection (BI) is a common cause of impairment of liver function in patients with cirrhosis, especially in the liver transplant candidates. These patients share an immunocompromised state and increased susceptibility to develop community and hospital-acquired infections. The changing epidemiology of BI, with an increase of multidrug resistant strains, especially in healthcare-associated settings, represents a critical issue both in the waiting list and in the post-operative management. This review focused on the role played by BI in patients awaiting liver transplantation, evaluating the risk of drop-out from the waiting list, the possibility to undergo liver transplantation after recovery from infection or during a controlled infection.
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spelling pubmed-58384412018-03-09 Management of bacterial infection in the liver transplant candidate Ferrarese, Alberto Zanetto, Alberto Becchetti, Chiara Sciarrone, Salvatore Stefano Shalaby, Sarah Germani, Giacomo Gambato, Martina Russo, Francesco Paolo Burra, Patrizia Senzolo, Marco World J Hepatol Review Bacterial infection (BI) is a common cause of impairment of liver function in patients with cirrhosis, especially in the liver transplant candidates. These patients share an immunocompromised state and increased susceptibility to develop community and hospital-acquired infections. The changing epidemiology of BI, with an increase of multidrug resistant strains, especially in healthcare-associated settings, represents a critical issue both in the waiting list and in the post-operative management. This review focused on the role played by BI in patients awaiting liver transplantation, evaluating the risk of drop-out from the waiting list, the possibility to undergo liver transplantation after recovery from infection or during a controlled infection. Baishideng Publishing Group Inc 2018-02-27 2018-02-27 /pmc/articles/PMC5838441/ /pubmed/29527258 http://dx.doi.org/10.4254/wjh.v10.i2.222 Text en ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Review
Ferrarese, Alberto
Zanetto, Alberto
Becchetti, Chiara
Sciarrone, Salvatore Stefano
Shalaby, Sarah
Germani, Giacomo
Gambato, Martina
Russo, Francesco Paolo
Burra, Patrizia
Senzolo, Marco
Management of bacterial infection in the liver transplant candidate
title Management of bacterial infection in the liver transplant candidate
title_full Management of bacterial infection in the liver transplant candidate
title_fullStr Management of bacterial infection in the liver transplant candidate
title_full_unstemmed Management of bacterial infection in the liver transplant candidate
title_short Management of bacterial infection in the liver transplant candidate
title_sort management of bacterial infection in the liver transplant candidate
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838441/
https://www.ncbi.nlm.nih.gov/pubmed/29527258
http://dx.doi.org/10.4254/wjh.v10.i2.222
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