Deep gray matter volume loss drives disability worsening in multiple sclerosis

OBJECTIVE: Gray matter (GM) atrophy occurs in all multiple sclerosis (MS) phenotypes. We investigated whether there is a spatiotemporal pattern of GM atrophy that is associated with faster disability accumulation in MS. METHODS: We analyzed 3,604 brain high‐resolution T1‐weighted magnetic resonance...

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Detalles Bibliográficos
Autores principales: Eshaghi, Arman, Prados, Ferran, Brownlee, Wallace J., Altmann, Daniel R., Tur, Carmen, Cardoso, M. Jorge, De Angelis, Floriana, van de Pavert, Steven H., Cawley, Niamh, De Stefano, Nicola, Stromillo, M. Laura, Battaglini, Marco, Ruggieri, Serena, Gasperini, Claudio, Filippi, Massimo, Rocca, Maria A., Rovira, Alex, Sastre‐Garriga, Jaume, Vrenken, Hugo, Leurs, Cyra E., Killestein, Joep, Pirpamer, Lukas, Enzinger, Christian, Ourselin, Sebastien, Wheeler‐Kingshott, Claudia A.M. Gandini, Chard, Declan, Thompson, Alan J., Alexander, Daniel C., Barkhof, Frederik, Ciccarelli, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838522/
https://www.ncbi.nlm.nih.gov/pubmed/29331092
http://dx.doi.org/10.1002/ana.25145

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