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Zika virus and pregnancy in Brazil: What happened?

The recent epidemic of Zika virus (ZIKV) infection in Central and South America is one of the most serious global public health emergencies since the Ebola outbreak in West Africa. In Brazil, especially in the north, northeast, and southeast parts of the country, the ZIKV outbreak is a cause of conc...

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Autores principales: Pereira, Alessandra Mendelski, Monteiro, Denise Leite Maia, Werner, Heron, Daltro, Pedro, Fazecas, Tatiana, Guedes, Bianca, Tonni, Gabriele, Peixoto, Alberto Borges, Júnior, Edward Araujo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838777/
https://www.ncbi.nlm.nih.gov/pubmed/29503261
http://dx.doi.org/10.4274/jtgga.2017.0072
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author Pereira, Alessandra Mendelski
Monteiro, Denise Leite Maia
Werner, Heron
Daltro, Pedro
Fazecas, Tatiana
Guedes, Bianca
Tonni, Gabriele
Peixoto, Alberto Borges
Júnior, Edward Araujo
author_facet Pereira, Alessandra Mendelski
Monteiro, Denise Leite Maia
Werner, Heron
Daltro, Pedro
Fazecas, Tatiana
Guedes, Bianca
Tonni, Gabriele
Peixoto, Alberto Borges
Júnior, Edward Araujo
author_sort Pereira, Alessandra Mendelski
collection PubMed
description The recent epidemic of Zika virus (ZIKV) infection in Central and South America is one of the most serious global public health emergencies since the Ebola outbreak in West Africa. In Brazil, especially in the north, northeast, and southeast parts of the country, the ZIKV outbreak is a cause of concern for pregnant women because ZIKV intrauterine infection has been found to be associated with multiple brain malformations and microcephaly. In Brazil, the number of newborns with confirmed microcephaly per year recorded during the ZIKV outbreak, has been approximately 15 times greater than previously reported. Considering that the infection is self-limiting and symptomatic, it is usually diagnosed at the time of routine prenatal scan, especially in the third trimester. In other cases, the disease is detected after childbirth through neuroimaging. This study provides an insight into the history and evolution of ZIKV in Brazil, including current knowledge concerning the transmission, diagnosis, and pathogenesis of the infection. In addition, this review describes the pre- and postnatal neuroimaging findings obtained using ultrasound, magnetic resonance imaging, and computed tomography.
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spelling pubmed-58387772018-03-08 Zika virus and pregnancy in Brazil: What happened? Pereira, Alessandra Mendelski Monteiro, Denise Leite Maia Werner, Heron Daltro, Pedro Fazecas, Tatiana Guedes, Bianca Tonni, Gabriele Peixoto, Alberto Borges Júnior, Edward Araujo J Turk Ger Gynecol Assoc Review The recent epidemic of Zika virus (ZIKV) infection in Central and South America is one of the most serious global public health emergencies since the Ebola outbreak in West Africa. In Brazil, especially in the north, northeast, and southeast parts of the country, the ZIKV outbreak is a cause of concern for pregnant women because ZIKV intrauterine infection has been found to be associated with multiple brain malformations and microcephaly. In Brazil, the number of newborns with confirmed microcephaly per year recorded during the ZIKV outbreak, has been approximately 15 times greater than previously reported. Considering that the infection is self-limiting and symptomatic, it is usually diagnosed at the time of routine prenatal scan, especially in the third trimester. In other cases, the disease is detected after childbirth through neuroimaging. This study provides an insight into the history and evolution of ZIKV in Brazil, including current knowledge concerning the transmission, diagnosis, and pathogenesis of the infection. In addition, this review describes the pre- and postnatal neuroimaging findings obtained using ultrasound, magnetic resonance imaging, and computed tomography. Galenos Publishing 2018-03 2018-03-01 /pmc/articles/PMC5838777/ /pubmed/29503261 http://dx.doi.org/10.4274/jtgga.2017.0072 Text en ©Copyright 2018 by the Turkish-German Gynecological Education and Research Foundation http://creativecommons.org/licenses/by/2.5/ Journal of the Turkish-German Gynecological Association
spellingShingle Review
Pereira, Alessandra Mendelski
Monteiro, Denise Leite Maia
Werner, Heron
Daltro, Pedro
Fazecas, Tatiana
Guedes, Bianca
Tonni, Gabriele
Peixoto, Alberto Borges
Júnior, Edward Araujo
Zika virus and pregnancy in Brazil: What happened?
title Zika virus and pregnancy in Brazil: What happened?
title_full Zika virus and pregnancy in Brazil: What happened?
title_fullStr Zika virus and pregnancy in Brazil: What happened?
title_full_unstemmed Zika virus and pregnancy in Brazil: What happened?
title_short Zika virus and pregnancy in Brazil: What happened?
title_sort zika virus and pregnancy in brazil: what happened?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838777/
https://www.ncbi.nlm.nih.gov/pubmed/29503261
http://dx.doi.org/10.4274/jtgga.2017.0072
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