A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy

BACKGROUND: Electrocardiographic measures of left ventricular hypertrophy (LVH) are used as predictors of cardiovascular risk. We combined linkage and association analyses to discover novel rare genetic variants involved in three such measures and two principal components derived from them. METHODS:...

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Detalles Bibliográficos
Autores principales: Silva, Claudia Tamar, Zorkoltseva, Irina V., Niemeijer, Maartje N., van den Berg, Marten E., Amin, Najaf, Demirkan, Ayşe, van Leeuwen, Elisa, Iglesias, Adriana I., Piñeros-Hernández, Laura B., Restrepo, Carlos M., Kors, Jan A., Kirichenko, Anatoly V., Willemsen, Rob, Oostra, Ben A., Stricker, Bruno H., Uitterlinden, André G., Axenovich, Tatiana I., van Duijn, Cornelia M., Isaacs, Aaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838853/
https://www.ncbi.nlm.nih.gov/pubmed/29506515
http://dx.doi.org/10.1186/s12920-018-0339-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838853/
https://www.ncbi.nlm.nih.gov/pubmed/29506515
http://dx.doi.org/10.1186/s12920-018-0339-9

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