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TNFα induces Ca(2+) influx to accelerate extrinsic apoptosis in hepatocellular carcinoma cells

BACKGROUND: Tumor necrosis factor-α has been proven an effective anticancer agent in preclinical studies. However, the translation of TNFα from research to clinic has been blocked by significant systemic toxicity and limited efficacy at maximal tolerated dose, which need urgently to be solved. METHO...

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Detalles Bibliográficos
Autores principales:	Zhu, Jianjun, Jin, Mingpeng, Wang, Jiaojiao, Zhang, Hui, Wu, Yousheng, Li, Deyang, Ji, Xiaoying, Yang, Hushan, Yin, Chun, Ren, Tingting, Xing, Jinliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838867/ https://www.ncbi.nlm.nih.gov/pubmed/29506556 http://dx.doi.org/10.1186/s13046-018-0714-6

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