Correlation of Serum Adiponectin and Leptin levels in Obesity and Type 2 Diabetes Mellitus

INTRODUCTION: Indian phenotype includes higher waist circumference despite lower body mass index, thereby making Indians more prone to diabetes and its complications. AIM: The present study aimed to analyze the serum levels of adiponectin and leptin in the participants with type 2 diabetes mellitus...

Descripción completa

Detalles Bibliográficos
Autores principales: Diwan, Arundhati G., Kuvalekar, Aniket A., Dharamsi, Siddharth, Vora, Aditya M., Nikam, Vivek A., Ghadge, Abhijit A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838920/
https://www.ncbi.nlm.nih.gov/pubmed/29535945
http://dx.doi.org/10.4103/ijem.IJEM_491_15
Descripción
Sumario:INTRODUCTION: Indian phenotype includes higher waist circumference despite lower body mass index, thereby making Indians more prone to diabetes and its complications. AIM: The present study aimed to analyze the serum levels of adiponectin and leptin in the participants with type 2 diabetes mellitus (T2DM) and obesity and their correlation with hypertension and dyslipidemia. MATERIALS AND METHODS: In the study, 50 diabetics and 50 controls aged between 40 and 60 years were included in the study. RESULTS: Adiponectin levels were significantly higher in diabetics than in nondiabetic participants irrespective of gender (P ≤ 0.04 in males, P ≤ 0.02 in females). Leptin levels were significantly higher in diabetics compared to nondiabetics (P ≤ 0.001) in both males and females. CONCLUSION: Adiponectin and leptin levels may be used as important clinical markers for T2DM and obesity.

Ejemplares similares